In the present study we investigated the sedative effect of rectally administered Bromazepam as an anesthetic premedicant. In 16 fearful children, aged from 2 to 4 years old, a dose of 0.2mg/kg of Bromazepam was adminitered rectally 2 hours before induction of general anesthesia. The patients underwent dental treatment under enflurane anesthesia. The average duration of anesthesia was 3 hours 25 minutes ±36 minutes. The results were as follows: 1) The sedative effect, especially antianxietic action was satisfactory in the operating room. 2) No remakable changes in respiratory or circulatory function was observed. 3) The induction of anesthesia was smooth due to the lack of the anxiety. 4) No delay of recovery from anestcesia was observed. 5) The adequate sedative effect was maintained after operation. 6) No complication or adverse effects were encountered. These results suggest the usefulness of Bromazepam Suppository for premedicant in fearful children.
小児前投薬としてbromazepam坐薬の使用経験
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