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多発性骨髄腫患者における骨吸収抑制剤関連顎骨壊死の保存的治療に成功した1例
https://mdu.repo.nii.ac.jp/records/2981
https://mdu.repo.nii.ac.jp/records/2981962545f0-1fa4-4191-8d04-d99cf42ee95f
名前 / ファイル | ライセンス | アクション |
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本文 (6.3 MB)
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Item type | 松本歯学/学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2022-05-10 | |||||
タイトル | ||||||
タイトル | 多発性骨髄腫患者における骨吸収抑制剤関連顎骨壊死の保存的治療に成功した1例 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 骨吸収抑制薬関連顎骨壊死 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ビスホスホネート製剤 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 保存的治療 | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
その他(別言語等)のタイトル | ||||||
その他のタイトル | Successful conservative treatment of anti–resorptive agent–related osteonecrosis of the jaw in a patient with multiple myeloma:A case report | |||||
著者 |
原, 美音
× 原, 美音× 堀部, 寛治× 松井, 龍一× 小山, 尚人× 尾崎, 友輝× 村上, 聡× 中村, 浩彰× 田口, 明× 酒井, 香生子× 吉成, 伸夫 |
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著者別名 |
HARA, MIKOTO
× HARA, MIKOTO× HORIBE, KANJI× MATSUI, RYUICHI× KOYAMA, NAOTO× OZAKI, YUKI× MURAKAMI, SATOSHI× NAKAMURA, HIROAKI× TAGUCHI, AKIRA× SAKAI, KAOKO× YOSHINARI, NOBUO |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Summary.Bone resorption inhibitors,such as bisphosphonates and denosumab,are widely used to treat bone lesions caused by disorders of bone metabolism,multiple myeloma,and bone metastases from solid tumors,and the occurrence of antiresorptive agentrelated osteonecrosis of the jaw (ARONJ) is increasing.Currently,surgical treatment is recommended;however,case reports are sparse and there is no established global consensus on treatment.We report the case of a 75–year–old female patient with osteonecrosis of the mandible following bisphosphonate administration for the treatment of multiple myeloma,who was cured by conservative treatment alone.The patient had multiple myeloma and,therefore,had been receiving bisphosphonates for about 24 months prior to her first visit to Matsumoto Dental University Hospital.During periodontal treatment,the patient underwent extraction of the left mandibular wisdom tooth.About 6 months later,bone exposure was observed in the same area,and coexisting osteomyelitis of the jaw was diagnosed.Conservative treatment involving oral hygiene instructions,several doses of antibacterial agents,and frequent rinses was chosen for the bone exposure.About 6 months after the start of such treatment,the decayed bone had disappeared,and after 7 months,the mucosa had completely sealed.Disappearance of the findings of osteomyelitis was assessed by MRI.The infection tended to spread during the clinical course of the disease,but improved with conservative treatment alone,and the exposed area of bone has since epithelialized.We reaffirmed the importance of collaboration and sharing information on the medical history and medications between physicians and dentists while treating patients with primary diseases indicated for bisphosphonates. | |||||
書誌情報 |
松本歯学 en : Journal of the Matsumoto Dental University Society 巻 47, 号 2, p. 125-135, 発行日 2022-05-10 |
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出版者 | ||||||
出版者 | 松本歯科大学学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2188-7233 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12684554 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |