<?xml version='1.0' encoding='UTF-8'?>
<OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd">
  <responseDate>2026-03-14T14:30:43Z</responseDate>
  <request metadataPrefix="jpcoar_1.0" verb="GetRecord" identifier="oai:mdu.repo.nii.ac.jp:00000635">https://mdu.repo.nii.ac.jp/oai</request>
  <GetRecord>
    <record>
      <header>
        <identifier>oai:mdu.repo.nii.ac.jp:00000635</identifier>
        <datestamp>2023-06-19T08:33:51Z</datestamp>
        <setSpec>1:34:114</setSpec>
      </header>
      <metadata>
        <jpcoar:jpcoar xmlns:datacite="https://schema.datacite.org/meta/kernel-4/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcndl="http://ndl.go.jp/dcndl/terms/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:jpcoar="https://github.com/JPCOAR/schema/blob/master/1.0/" xmlns:oaire="http://namespace.openaire.eu/schema/oaire/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:rioxxterms="http://www.rioxx.net/schema/v2.0/rioxxterms/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns="https://github.com/JPCOAR/schema/blob/master/1.0/" xsi:schemaLocation="https://github.com/JPCOAR/schema/blob/master/1.0/jpcoar_scm.xsd">
          <dc:title>ヒト歯根膜線維芽細胞におけるメカニカルストレスによるIL-1β, MMP-1(collagenase), collagen type-IのmRNAの発現について</dc:title>
          <dcterms:alternative>IL-1β, MMP-1 and Collagen Type-I mRNA Expression of Stretched Human Periodontal Ligament Fibroblasts</dcterms:alternative>
          <jpcoar:creator>
            <jpcoar:creatorName>大嶋, 嘉久</jpcoar:creatorName>
            <jpcoar:creatorName>上松, 節子</jpcoar:creatorName>
            <jpcoar:creatorName>平岡, 行博</jpcoar:creatorName>
            <jpcoar:creatorName>栗原, 三郎</jpcoar:creatorName>
          </jpcoar:creator>
          <jpcoar:subject subjectScheme="Other">メカニカルストレス</jpcoar:subject>
          <jpcoar:subject subjectScheme="Other">ヒト歯根膜線維芽細胞</jpcoar:subject>
          <jpcoar:subject subjectScheme="Other">IL-1β</jpcoar:subject>
          <jpcoar:subject xml:lang="en" subjectScheme="Other">MMP-1</jpcoar:subject>
          <jpcoar:subject xml:lang="en" subjectScheme="Other">collagen type-I</jpcoar:subject>
          <datacite:description descriptionType="Other">application/pdf</datacite:description>
          <datacite:description descriptionType="Abstract">Continuous stretched tension force was applied to human periodontal ligament fibroblasts to determine the effect of this stimulus on the relative expression of IL-1β, matrix metalloproteinase (MMP)-1 and collagen type-ImRNA. The steady-state mRNA level for MMP-1 and collagen type-ImRNA were determined, however IL-1β mRNA was not detected. The results indicate that continuous stretched force in this present study was clinically adapted as orthodontic force but weak to determine the expression of IL-1β mRNA.</datacite:description>
          <dc:publisher>松本歯科大学学会</dc:publisher>
          <datacite:date dateType="Issued">2002-04-30</datacite:date>
          <dc:language>jpn</dc:language>
          <dc:type rdf:resource="http://purl.org/coar/resource_type/c_6501">journal article</dc:type>
          <oaire:version rdf:resource="http://purl.org/coar/version/c_970fb48d4fbd8a85">VoR</oaire:version>
          <jpcoar:identifier identifierType="URI">https://mdu.repo.nii.ac.jp/records/635</jpcoar:identifier>
          <jpcoar:sourceIdentifier identifierType="NCID">AN00232590</jpcoar:sourceIdentifier>
          <jpcoar:sourceIdentifier identifierType="ISSN">0385-1613</jpcoar:sourceIdentifier>
          <jpcoar:sourceTitle>松本歯学</jpcoar:sourceTitle>
          <jpcoar:volume>28</jpcoar:volume>
          <jpcoar:issue>1</jpcoar:issue>
          <jpcoar:pageStart>7</jpcoar:pageStart>
          <jpcoar:pageEnd>12</jpcoar:pageEnd>
          <jpcoar:file>
            <jpcoar:URI label="matsumoto_shigaku_28-01-02.pdf">https://mdu.repo.nii.ac.jp/record/635/files/matsumoto_shigaku_28-01-02.pdf</jpcoar:URI>
            <jpcoar:mimeType>application/pdf</jpcoar:mimeType>
            <jpcoar:extent>723.4 kB</jpcoar:extent>
            <datacite:date dateType="Available">2012-05-24</datacite:date>
          </jpcoar:file>
        </jpcoar:jpcoar>
      </metadata>
    </record>
  </GetRecord>
</OAI-PMH>
