@article{oai:mdu.repo.nii.ac.jp:00001011,
 author = {川上, 敏行 and 安東, 基善 and 吉河, 靖 and 宇治, 英世 and 長谷川, 博雅 and 枝, 重夫},
 issue = {2},
 journal = {松本歯学},
 month = {Aug},
 note = {application/pdf, Tissue reactions to subcutaneously embedded squalane fluid were histopathologically investigated, using twenty six female adult SD rats. The experimental periods ranged from one day to six weeks. The results are as follows: 1) No abnormalities appeared in the entire body of all experimental rats compared with the control animals by macroscopic observations during the experimental periods. 2) Histopathologically, granulation tissue formation with a slight inflammatory cell infiltration was elicited by the squalane fluid, although no degeneration and necrosis were recognized in the embedded area. 3) Some of the squalane were phagocytosed by macrophages in the granulation tissue, and no encapsulation was observed. 4) Accordingly, these data lead us to believe that squalane fluid is usable as a drug carrier inside the body.},
 pages = {117--122},
 title = {ラットの皮下組織内に埋入したスクアランに対する組織反応},
 volume = {18},
 year = {1992}
}