@article{oai:mdu.repo.nii.ac.jp:00001168,
 author = {宮沢, 裕夫 and 大隈, 敦子 and 今西, 孝博 and 半戸, 茂友},
 issue = {1},
 journal = {松本歯学},
 month = {Apr},
 note = {application/pdf, The mouth, which is an open organ, is constantly covered with secretory and serum antibodies. These antibodies, which are resistant to protein-dissolving enzymes and bacterial protein-dissolving enzymes, are believed to prevent the attachment of oral bacteria such as Str. mutans on the tooth surface, and to control their multiplication by working as neutralizing or cohesive antibodies. In a basic study of anticaries immunity, Taubman, Michaleck and others suggested the existance of secretory type IgA acted clearly as an anticaries agent. From a clinical viewpoint, Arnold and others suggested the existence of secretory type IgA which acted against Str. mutans in the colostrum and saliva. In this study we investigated the relationship between Ig in the colostrum and the amount of Ig and pH in the infant saliva, as a preparatory study for examining the signifcance of the amount of Ig in controling the activity of caries and the adhesion of bacteria in the mouth. The results obtained are as follows. 1) The SRID (Single Radial Immunodiffuson) method was valuable for measuring the amount of Ig in saliva. 2) In ragard to the amount of Ig in the saliva, no significant difference was recognized between batches prior to processing and those receiving no processing. 3) No significant difference was recognized in the amount of Ig within natural saliva and saliva subjected to stimulus. 4) Sexual difference had no significant effect on the amount of Ig in the saliva.},
 pages = {38--45},
 title = {齲蝕免疫に関する基礎的研究},
 volume = {15},
 year = {1989}
}