{"created":"2023-06-19T07:38:14.205092+00:00","id":1195,"links":{},"metadata":{"_buckets":{"deposit":"83c5ae6a-cb5e-4dcf-baef-4ef8bb536bab"},"_deposit":{"created_by":3,"id":"1195","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"1195"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00001195","sets":["1:47:77"]},"author_link":["0"],"item_2_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Enamel Proteins : Biochemistry of amelogenin(s) and enamelin(s)"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1988-08-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"153","bibliographicPageStart":"139","bibliographicVolumeNumber":"14","bibliographic_titles":[{"bibliographic_title":"松本歯学"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"During the process of enamel formation by ameloblasts the extracellular matrix that is secreted first is relatively high in protein (20%), but, this percentage decreases during the maturation phase to less than 1%. Enamel proteins may be divided into two classes designated amelogenins and enamelins based upon their solubility, affinity to hydroxyapatite, amino acid compositions, and apparent molecular weight. Neutral salt or guanidine-HCl soluble amelogenins gradually hydrolyzes into small peptides during hydroxyapatite crystal formation, while enamelins, which solubilize after EDTA decalcification, remain in apatite crystal after maturation. In this paper, biochemical studies on the amelogenins and the enamelins are described. This includes extraction from tissue preparation, purification procedure, primary and secondary structures of amelogenin, antibody production and their cross reactivity, amelogenin CDNA cloning and analysis of its nucleotides sequence, and the function of both proteins on crystal formation.","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"松本歯科大学学会"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00232590","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-1613","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"原田, 実"}],"nameIdentifiers":[{"nameIdentifier":"0","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2012-05-24"}],"displaytype":"detail","filename":"matsumoto_shigaku_14-02-01.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"matsumoto_shigaku_14-02-01.pdf","url":"https://mdu.repo.nii.ac.jp/record/1195/files/matsumoto_shigaku_14-02-01.pdf"},"version_id":"f79cbb85-af43-4d3e-bc6f-549106ba42be"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"エナメルタンパク質","subitem_subject_scheme":"Other"},{"subitem_subject":"アメロゲニン","subitem_subject_scheme":"Other"},{"subitem_subject":"エナメリン","subitem_subject_scheme":"Other"},{"subitem_subject":"生化学","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"エナメルタンパク質 : アメロゲニンとエナメリンの生化学","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"エナメルタンパク質 : アメロゲニンとエナメリンの生化学"}]},"item_type_id":"2","owner":"3","path":["77"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-05-24"},"publish_date":"2012-05-24","publish_status":"0","recid":"1195","relation_version_is_last":true,"title":["エナメルタンパク質 : アメロゲニンとエナメリンの生化学"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T08:19:29.178369+00:00"}