{"created":"2023-06-19T07:38:25.874619+00:00","id":1395,"links":{},"metadata":{"_buckets":{"deposit":"598c89a1-cf09-4eff-ac7f-aa86594d23ae"},"_deposit":{"created_by":3,"id":"1395","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"1395"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00001395","sets":["1:51:67"]},"author_link":["0"],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1984-06-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"23","bibliographicPageStart":"17","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"松本歯学"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Effects of sodium fluoride (NaF) on the bullfrog heart were investigated. NaF (10 mM) inhibited the autonomic heart contraction, reducing the heart rate. This inhibitory action was recovered by per fusion with 2-Ca^<++> Ringer's solution. The twitch tension of auricular muscle was reduced by 2 mM NaF as well as 1 mM sodium oxalate and low-Ca^<++> Ringer, but the latter two were less effective than the former. However, NaF (5 mM) induced a rise in resting tension similar to that in the case of DNP application. ATP, adrenaline, and theophylline all reversed the inhibitory action of NaF, while both DNP and iodo acetic acid promoted it. NaF (5 mM) decreased the tension of Na^+-deficient contracture. The results obtained suggest that the reduction in the heart motility by NaF might be caused by the following mechanism : Inhibition of Ca^<++> influx into the myocardial cell as a result of both decrease in the extracellular Ca^<++> concentration and inhibition of ATP production and the Na^+-Ca^<++> exchange.","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"松本歯科大学学会"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00232590","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-1613","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"HATTORI, TOSHIMI"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2012-05-24"}],"displaytype":"detail","filename":"matsumoto_shigaku_10-01-02.pdf","filesize":[{"value":"386.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"matsumoto_shigaku_10-01-02.pdf","url":"https://mdu.repo.nii.ac.jp/record/1395/files/matsumoto_shigaku_10-01-02.pdf"},"version_id":"50ad48db-e170-41c3-ae42-a5499fd152c3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"sodium fluoride","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"frog heart contraction","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Ca^&lt;++&gt; influx","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Na^+-Ca^&lt;++&gt;","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"exchange mechanism","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of Sodium Fluoride on Frog Heart Motility","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of Sodium Fluoride on Frog Heart Motility","subitem_title_language":"en"}]},"item_type_id":"2","owner":"3","path":["67"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-05-24"},"publish_date":"2012-05-24","publish_status":"0","recid":"1395","relation_version_is_last":true,"title":["Effects of Sodium Fluoride on Frog Heart Motility"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T08:14:49.016474+00:00"}