{"created":"2023-06-19T07:37:08.373013+00:00","id":141,"links":{},"metadata":{"_buckets":{"deposit":"39a2c8fd-8acb-4a4a-93e1-17a0bb730fdd"},"_deposit":{"created_by":3,"id":"141","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"141"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00000141","sets":["1:26:27"]},"author_link":["0"],"item_2_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Study on the Enzymes of Acid-mucopolysaccharides and Lecithin Degradation of Oral Anaerobic Microorganisms Produced Experimental Mixed Infection"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1975-12-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"21","bibliographicPageStart":"11","bibliographicVolumeNumber":"1","bibliographic_titles":[{"bibliographic_title":"松本歯学"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"It was found by Takazoe and Nakamura that transmissable experimental mixed infection was produced by oral anaerobic three species. Various acid-mucopolysaccharides degradating activities of heparinase-producing Bacteroides, Bacteroides melaninogenicus and Propionibacterium acnes respectively, and the lecithin degradating factor of the latter microorganism were studied. Results obtaind are as follows. 1. Heparinase-producing Bacteroides was found to degrade heparin, chondroitin sulfate and hyaluronic acid in the substrate added Trypticase broth, respectively. Propionibacterium acnes degradated the latter two substrates except for heparin in this broth, but Bacteroides melaninogenicus did not affect any acid-mucopolysaccharides. 2. As for degradation activity of crude enzyme extracted from two microorganisms having degradating ability, heparin and chondroitin sulfate degradation activities of heparinase-producing Bacteroides appeared only by both substrates added to preculture broth, but hyaluronic acid degradation was not affected with substrate added. The enzyme of Propionibacterium acnes was produciable. 3. Egg yolk reaction factor of Propionibacterium acnes was found to degrade lecithin by plate method, paper-chromatography and increase of titration value with N/100 NaOH solution of reaction mixture. The factor was released into the medium and was precipitated by ammonium sulfate. The lecithin hydrolytic activity of this fraction was not　dializable and inactive at 65℃. The evidence from serial experiments indicated that this factor was an enzyme, lecithinase, possessing characters as optimal reaction at pH 6.5～7.0 and 37℃. 4. Possible role of three anaerobes producing mixed infection in the etiology of Periodontal disease was discussed based upon degradating enzymes of extensive substrates of those species including collagen-splitter, Bacteroides melaninogenicus.","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"松本歯科大学学会"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00232590","subitem_source_identifier_type":"NCID"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中村, 武"},{"creatorName":"杉中, 芳幸"},{"creatorName":"小幡, 直樹"},{"creatorName":"青木, 宣夫"}],"nameIdentifiers":[{"nameIdentifier":"0","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2012-05-23"}],"displaytype":"detail","filename":"matsumoto_shigaku_01-01-06.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"matsumoto_shigaku_01-01-06.pdf","url":"https://mdu.repo.nii.ac.jp/record/141/files/matsumoto_shigaku_01-01-06.pdf"},"version_id":"c54ecd5e-8ab0-40fd-b3b9-a308f3ba823e"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"混合感染能を有する口腔内嫌気性菌の酸性ムコ多糖体と脂質分解酵素に関する研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"混合感染能を有する口腔内嫌気性菌の酸性ムコ多糖体と脂質分解酵素に関する研究"}]},"item_type_id":"2","owner":"3","path":["27"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-05-23"},"publish_date":"2012-05-23","publish_status":"0","recid":"141","relation_version_is_last":true,"title":["混合感染能を有する口腔内嫌気性菌の酸性ムコ多糖体と脂質分解酵素に関する研究"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T08:44:53.554751+00:00"}