{"created":"2023-06-19T07:38:43.218515+00:00","id":2233,"links":{},"metadata":{"_buckets":{"deposit":"f62aa9c4-25f0-49d5-ae8a-bbce81ec98d8"},"_deposit":{"created_by":3,"id":"2233","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2233"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00002233","sets":["170:177"]},"author_link":["2140","2144","2143","2145","2142","2141","2138","2139"],"item_10006_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Influence of local anesthetics on tissue blood flow−The change of skin blood flow by subcutaneous injection into the back skin of rabbits−"}]},"item_10006_biblio_info_28":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"119","bibliographicPageStart":"110","bibliographicVolumeNumber":"39","bibliographic_titles":[{"bibliographic_title":"松本歯学"}]}]},"item_10006_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ohno, Tadao"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Taniyama, Kiichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishida, Maiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shibutani, Tohru"}],"nameIdentifiers":[{}]}]},"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2014-03-06"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与大学","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"松本歯科大学"}],"subitem_degreegrantor_identifier":[{}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（歯学）"}]},"item_10006_description_10":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_description":"2013","subitem_description_type":"Other"}]},"item_10006_description_12":{"attribute_name":"報告番号","attribute_value_mlt":[{"subitem_description":"甲第148号","subitem_description_type":"Other"}]},"item_10006_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We examined the influence of lidocaine, mepivacaine, ropivacaine , bupivacaine , and levobupivacaine on skin blood flow in rabbits using a laser Doppler blood flowmeter. New Zealand White rabbits were anesthetized with sodium thiopental. 0.2 ml of 0.125～ 2.0% lidocaine, 0.125～3.0% mepivacaine, 0.125～0.75% ropivacaine, 0.125～0.5% bupivacaine, 0.125～0.75% levobupivacaine, 2.0% lidocaine with adrenaline (A) (1/80,000), and 3.0% propitocaine with felypressin (0.03 IU) were injected subcutaneously into the back skin of the rabbit’s. Physiological saline (0.2 ml) was injected as a control. We measured the skin blood flow using a laser Doppler blood flowmeter before and 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 7, 8, 9, and 10 minutes after the injection. The blood flow after the injection of each local anesthetic was converted into a percentage of the control value (before injection). The mean values of the skin blood flow before the injection in each group showed no significant differences. The skin blood flow was increased 30 seconds after the injection of physiological saline and showed no significant changes from 1 to 10 minutes after the injection. The skin blood flow was significantly increased by the subcutaneous injection of 0.125, 0.25, 0.5, 0.75, 1.0, and 2.0% lidocaine, 1.0, 2.0, and 3.0% mepivacaine, 0.125, 0.25, and 0.5% bupivacaine, and 0.75% levobupivacaine. The skin blood flow was significantly decreased by the injection of 0.125, 0.25, 0.5, and 0.75% mepivacaine, 0.125, 0.25, 0.5, and 0.75% ropivacaine, 0.125, 0.25, and 0.5% levobupivacaine. Lidocaine and bupivacaine increased the skin blood flow dependent on their concentration. On the other hand, ropivacaine decreased the skin blood flow dependent on its concentration. Mepivacaine decreased the skin blood flow at concentrations lower than 0.75% and increased it at a concentration higher than 1.0%. Levobupivacaine decreased the skin blood flow at concentrations lower than 0.5%, and increased it at those higher than 0.75%. The 0.5% bupivacaine and 2.0% lidocaine led to the most marked increase in skin blood flow, and 2.0% lidocaine?A and 0.75% ropivacaine led to the most marked decrease.","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_22":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第148号"}]},"item_10006_relation_14":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"雑誌掲載論文(電子版)"}]}]},"item_10006_relation_15":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"松本歯科大学リポジトリ"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://mdu.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=1822&item_no=1&page_id=13&block_id=17","subitem_relation_type_select":"URI"}}]},"item_10006_relation_25":{"attribute_name":"NII論文ID","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"120005381241","subitem_relation_type_select":"NAID"}}]},"item_10006_relation_26":{"attribute_name":"医中誌ID","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"2014204038","subitem_relation_type_select":"ICHUSHI"}}]},"item_10006_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2016. 松本歯科大学学会"}]},"item_10006_source_id_27":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2188-7233","subitem_source_identifier_type":"ISSN"}]},"item_10006_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大野, 忠男"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"谷山, 貴一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"石田, 麻依子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"澁谷, 徹"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2014-07-22"}],"displaytype":"detail","filename":"33602_A000175_honbun.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"本文","url":"https://mdu.repo.nii.ac.jp/record/2233/files/33602_A000175_honbun.pdf"},"version_id":"f4c43385-5f84-4fd6-ad14-f550958c39d1"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2014-07-22"}],"displaytype":"simple","filename":"33602_A000175_shinsa-yoshi.pdf","filesize":[{"value":"316.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"内容の要旨および審査の結果の要旨 ","url":"https://mdu.repo.nii.ac.jp/record/2233/files/33602_A000175_shinsa-yoshi.pdf"},"version_id":"1a8eb771-735d-41df-af04-eb80b99097ae"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"局所麻酔薬","subitem_subject_scheme":"Other"},{"subitem_subject":"皮膚組織血流量","subitem_subject_scheme":"Other"},{"subitem_subject":"レーザードップラー血流計","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"局所麻酔薬の組織血流量への影響−家兎背部への皮下注射による皮膚血流量の変化−","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"局所麻酔薬の組織血流量への影響−家兎背部への皮下注射による皮膚血流量の変化−"}]},"item_type_id":"10006","owner":"3","path":["177"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-07-15"},"publish_date":"2014-07-15","publish_status":"0","recid":"2233","relation_version_is_last":true,"title":["局所麻酔薬の組織血流量への影響−家兎背部への皮下注射による皮膚血流量の変化−"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-19T07:58:35.532062+00:00"}