{"created":"2023-06-19T07:38:44.490509+00:00","id":2268,"links":{},"metadata":{"_buckets":{"deposit":"78f3b1b4-bd82-42e3-b534-9d32cf24a2ee"},"_deposit":{"created_by":3,"id":"2268","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2268"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00002268","sets":["1:198:199"]},"author_link":["2323","2314","2320","2313","2324","2318","2310","2308","2306","2317","2301","2316","2304","2309","2322","2302","2305","2321","2311","2303","2307","2312","2315","2319"],"item_10001_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Porphyromonas gingivalis スーパーオキシドジスムターゼの構造における72位Leu をTrp に置換した影響"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-06-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"25","bibliographicPageStart":"19","bibliographicVolumeNumber":"40","bibliographic_titles":[{"bibliographic_title":"松本歯学"},{"bibliographic_title":"Journal of the Matsumoto Dental University Society","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小町谷, 美帆"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"溝上, 真也"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"三原, 正志"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大澤, 雅樹"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"菊池, 有一郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"上松, 節子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"平井, 要"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大久保, 裕一郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"黒岩, 昭弘"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山田, 一尋"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山倉, 文幸"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"平岡, 行博"}],"nameIdentifiers":[{}]}]},"item_10001_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Porphyromonas gingivalis contains a single constitutive superoxide dismutase (SOD) that is active with either iron or manganese at the active site. The aim of this work was to evaluate the effect of the Leu ₇2 to Trp mutation on the structure of P. gingivalis SOD (Pg SOD) using lectrophoretic characterization. Leu ₇2, which is located near the active site metal, is substituted with Trp in aligned amino acid sequences of iron–containing SOD. The results of electrophoretic characterization and the expressed activity of mutant SOD suggest that mutant SOD have the same gross structure as wild–type SOD. We herein conclude that the integrity of Leu ₇2 is a necessary requisite for the metal–tolerant activity of Pg SOD.","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"松本歯科大学学会"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-1613","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KOMACHIYA, MIHO"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MIZOUE, SHINYA"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MIHARA, MASASHI"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"OSAWA, MASAKI"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KIKUCHI, YUICHIRO"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"UEMATSU, SETSUKO"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"UEMATSU, SETSUKO"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"OKUBO, YUICHIRO"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KUROIWA, AKIHIRO"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YAMADA, KAZUHIRO"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YAMAKURA, FUMIYUKI"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"HIRAOKA, B.YUKIHIRO"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2014-09-11"}],"displaytype":"detail","filename":"matsumoto_shigaku40-1-03.pdf","filesize":[{"value":"2.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"matsumoto_shigaku40-1-03.pdf","url":"https://mdu.repo.nii.ac.jp/record/2268/files/matsumoto_shigaku40-1-03.pdf"},"version_id":"f9d4f4fc-e418-4bac-a92d-e63183daabac"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"site–directed mutagenesis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"superoxide dismutase","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Porphyromonas gingivalis","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effect of substituting Trp for Leu at position 72 on the structure of Porphyromonas gingivalis superoxide dismutase","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effect of substituting Trp for Leu at position 72 on the structure of Porphyromonas gingivalis superoxide dismutase","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"3","path":["199"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-09-11"},"publish_date":"2014-09-11","publish_status":"0","recid":"2268","relation_version_is_last":true,"title":["Effect of substituting Trp for Leu at position 72 on the structure of Porphyromonas gingivalis superoxide dismutase"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-19T08:06:31.126169+00:00"}