{"created":"2023-06-19T07:38:45.326717+00:00","id":2280,"links":{},"metadata":{"_buckets":{"deposit":"23d7d54f-71f5-4f9a-a100-a9464d4ea30b"},"_deposit":{"created_by":3,"id":"2280","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2280"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00002280","sets":["178:204","193:194:195","193:208:276","193:235:270","193:236:238"]},"author_link":["2375","2376","2377","2378"],"item_10001_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"リポ多糖類処置したヒト歯肉線維芽細胞はPGE2を連続的に産生する"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-10-20","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"124","bibliographicPageStart":"121","bibliographicVolumeNumber":"17","bibliographic_titles":[{},{"bibliographic_title":"Journal of Hard Tissue Biology","bibliographic_titleLang":"en"}]}]},"item_10001_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The aim of this study was to examine whether human gingival fibroblasts (HGFs) sustain to produce prostaglandin E2 (PGE2) in the presence of lipopolysaccharide (LPS). HGFs were treated with or without 10 ng/ml of LPS from Porphyromonas gingivalis (PgLPS) for 7 days collecting the culture supernatants for every 24 h, and PGE2 concentration in the supernatants was measured by ELISA. HGFs produced PGE2 at low level without PgLPS treatment. In contrast, HGFs continuously produce PGE2 with PgLPS treatment. At each day, the amount of PGE2 production by HGFs with PgLPS treatment was higher than that without treatment. These results demonstrate that the characteristic of HGFs, which continuously produce PGE2 in the presence of LPS, sustains inflammatory response in periodontal disease.","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Hard Tissue Biology Network Association(JHTBNet)"}]},"item_10001_relation_12":{"attribute_name":"NII論文ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"110007081299","subitem_relation_type_select":"NAID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"info:doi/10.2485/jhtb.17.121"}],"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2485/jhtb.17.121","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"J-STAGE"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://doi.org/10.2485/jhtb.17.121","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_24":{"attribute_name":"医中誌ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"2009187331","subitem_relation_type_select":"ICHUSHI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright © 2008 by The Hard Tissue Biology Network Association(JHTBNet) "}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11074332","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1880-828X","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ARA, TOSHIAKI"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"FUJINAMI, YOSHIAKI"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"IMAMURA, YASUHIRO"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"WANG, PAO-LI"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2014-10-06"}],"displaytype":"detail","filename":"2014-005_JA.pdf","filesize":[{"value":"45.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"2014-005_JA.pdf","url":"https://mdu.repo.nii.ac.jp/record/2280/files/2014-005_JA.pdf"},"version_id":"07bad5c5-0f85-4f79-9552-803cf9a9d8e8"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"human gingival fibroblast","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Lipopolysaccharide","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Prostaglandin E2","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Lipopolysaccharide-Treated Human Gingival Fibroblasts Continuously Produce PGE2","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Lipopolysaccharide-Treated Human Gingival Fibroblasts Continuously Produce PGE2","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"3","path":["195","204","238","270","276"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-10-06"},"publish_date":"2014-10-06","publish_status":"0","recid":"2280","relation_version_is_last":true,"title":["Lipopolysaccharide-Treated Human Gingival Fibroblasts Continuously Produce PGE2"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-19T07:59:23.062683+00:00"}