{"created":"2023-06-19T07:37:14.641826+00:00","id":255,"links":{},"metadata":{"_buckets":{"deposit":"1de6706f-fbaf-4ffe-a0c9-ba1821b38acc"},"_deposit":{"created_by":3,"id":"255","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"255"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00000255","sets":["1:11:59"]},"author_link":["0"],"item_2_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Antibacterial Activity of the Black Pigment (Hematin) of Bacteroides melaninogenicus"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1980-06-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"108","bibliographicPageStart":"100","bibliographicVolumeNumber":"6","bibliographic_titles":[{"bibliographic_title":"松本歯学"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"From cells of Bacteroides melaninogenicus, isolated from human gingival crevice deposits, the black pigment was extracted by the established methods. The extracted pigment was identified as hematin upon examination of its various properties. Extracted hematin from five different strains inhibited the growth of the many kinds of Gram positive bacterial species, in which Actionmyces viscosus and Barterionema matruchotii were very susceptible (Minimum Inhibitory Concentration=MIC, 25.0μg/ml) as Streptococcus mutans. In other species, Actinomyces, Strep, mitts, Corynebacterium parvlum, and Propionibacterium acnes were moderately sensitive. They were inhibited at a concentration of 50.0μg/ml. The same results were shown with the use of authentic hematin. There was a proportional relationship between hematin concentration and the squares of diameters of inhibitory zones on agar plates. Other tested strains grew almost normally even if they were exposed to hematin at concentration over 200μg/ml. A similar antimicrobial activity as hematin was detected, if not so markedly, in the pus obtained from inflammatory lesion produced by experimental mixed infection including B. melaninogenicus.","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"松本歯科大学学会"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00232590","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-1613","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中村, 武"},{"creatorName":"藤村, 節夫"},{"creatorName":"金川, 直博"}],"nameIdentifiers":[{"nameIdentifier":"0","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2012-05-23"}],"displaytype":"detail","filename":"matsumoto_shigaku_06-01-12.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"matsumoto_shigaku_06-01-12.pdf","url":"https://mdu.repo.nii.ac.jp/record/255/files/matsumoto_shigaku_06-01-12.pdf"},"version_id":"17718968-5d50-4c2e-bb24-52ba35a10dd7"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Bacteroides melaninogenicusのblak pigment (hematin)の抗菌活性","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Bacteroides melaninogenicusのblak pigment (hematin)の抗菌活性"}]},"item_type_id":"2","owner":"3","path":["59"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-05-23"},"publish_date":"2012-05-23","publish_status":"0","recid":"255","relation_version_is_last":true,"title":["Bacteroides melaninogenicusのblak pigment (hematin)の抗菌活性"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T08:42:28.228691+00:00"}