@article{oai:mdu.repo.nii.ac.jp:00002606, author = {MAKI, SHIGERU and ARA, TOSHIAKI and TAKEUCHI, YURI and IWAI, YUKIKO and YOSHINARI, NOBUO and SATOH, AKIRA and MAEJIMA, SHINYA and 牧, 茂 and 荒, 敏昭 and 竹内, 由里 and 岩井, 由紀子 and 吉成, 伸夫 and 佐藤, 晶 and 前島, 信也}, issue = {2}, journal = {松本歯学, Journal of the Matsumoto Dental University Society}, month = {Dec}, note = {application/pdf, To clarify risk factors for periodontal disease from the viewpoints of physiology, blood biochemistry, and nutrition, a survey involving 364 persons (224 males, 140 females) who consulted the Medical Examination Center of Matsumoto Dental University Hospital was conducted. The pathogenesis of periodontal disease was investigated using the maximum Community Periodontal Index (CPI) and Attachment Loss (AL) values, and their distributions with respect to the sex were analyzed using Wilcoxonʼs rank sum test. Based on the CPI and AL values, the subjects were divided into 3 groups: healthy (0), mild (1–2), and severe (3–4). The mean values obtained from the physiological, dental, blood biochemical, and nutritional findings in the 3 groups were analyzed using the multiple comparison test. Furthermore, their distributions with respect to sex and smoking in the 3 groups were analyzed using Fisherʼs direct probability test. A p–value of 0.05 was regarded as significant. Factors influencing the CPI included the sex (male), body mass index (BMI), abdominal circumference, diastolic blood pressure, AL, alanine aminotransferase (ALT), fasting blood glucose, neutral fat, HDL cholesterol, and smoking. Factors influencing the AL included the sex (male), age, current number of teeth, CPI, lipid intake, manganese intake, vitamin C intake, monounsaturated fatty acid intake, polyunsaturated fatty acid intake, n–6 fatty acid intake, fruit intake, and smoking. The results suggest that the physiological, blood biochemical, and nutritional states are involved in the pathogenesis of periodontal disease. The CPI was associated with metabolic error in the presence of metabolic syndrome. There was an association between the AL and diet as an environmental factor.}, pages = {91--103}, title = {歯周疾患の病態に関する栄養学的視点を含めた総合的分析}, volume = {42}, year = {2016} }