@article{oai:mdu.repo.nii.ac.jp:00000266, author = {倉橋, 寿 and 都築, 新太郎 and 前橋, 浩 and 北村, 豊 and 坂本, 茂 and 有賀, 功 and 鹿毛, 俊孝 and 千野, 武広}, issue = {2}, journal = {松本歯学}, month = {Dec}, note = {application/pdf, A fluorometric method has been developed for the determination of cephalexin in plasma and urine. A fluorescent product was formed when samples containing cephalexin were heated for an hour at 100℃ and pH 1.0. The fluorescence was determined in sodium hydroxide solution (pH 13.0) at excitation and emission wavelengths of 355 and 432 nm, respectively. Only 0.1ml of plasma or urine was required, and concentrations of cephalexin as small as 0.1mcg/ml might be determined. In plasma samples from male rabbits taken over a 6-hr-period after an oral administration of 100mg/kg of cephalexin, and urinary samples from human male volunteers taken over a 6-hr-period after an oral administration of 500mg of cephalexin, were investigated using this new method.}, pages = {169--172}, title = {螢光法による体液中セファレキシンの定量法の検討}, volume = {6}, year = {1980} }