{"created":"2023-06-19T07:39:02.572418+00:00","id":2694,"links":{},"metadata":{"_buckets":{"deposit":"7ec62028-bd3f-4478-baa0-2c6b1cb9d213"},"_deposit":{"created_by":3,"id":"2694","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2694"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00002694","sets":["178:371","193:201:378","193:234:268"]},"author_link":["3825","3827","3826","3824"],"item_10001_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Bone-remodeling mechanism regulating by sclerostin"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"173","bibliographicPageStart":"169","bibliographicVolumeNumber":"30","bibliographic_titles":[{"bibliographic_title":"THE BONE"}]}]},"item_10001_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KOIDE, MASANORI"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"UDAGAWA, NOBUYUKI"}],"nameIdentifiers":[{}]}]},"item_10001_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"近年、骨代謝における骨細胞の役割が注目されている。骨に埋め込まれた骨細胞は、力学負荷を感知すると考えられている。運動による力学負荷は骨量の増加や維持に重要である。逆に、微小重力やベッドレストにより骨量は減少する。しかし、どのようなメカニズムで骨量が調整されるのかは不明であった。本稿では、力学負荷と副甲状腺ホルモンによる骨細胞や骨芽細胞を介した骨量調節作用および骨細胞が産生する骨形成阻害因子であるスクレロスチンの発現制御について概説する。","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"(株)メディカルレビュー社"}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"メディカルオンライン"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://mol.medicalonline.jp/archive/select?jo=ai1bonee","subitem_relation_type_select":"URI"}}]},"item_10001_relation_24":{"attribute_name":"医中誌ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"2016292076","subitem_relation_type_select":"ICHUSHI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2016 (株)メディカルレビュー社"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10080921","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0914-7047","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小出, 雅則"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"宇田川, 信之"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-07"}],"displaytype":"detail","filename":"2017-ja-001.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"本文","url":"https://mdu.repo.nii.ac.jp/record/2694/files/2017-ja-001.pdf"},"version_id":"82f3d4ac-bae4-4e87-811a-289544ebc5b2"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"骨代謝","subitem_subject_scheme":"Other"},{"subitem_subject":"骨細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"骨形成","subitem_subject_scheme":"Other"},{"subitem_subject":"スレロスチン","subitem_subject_scheme":"Other"},{"subitem_subject":"副甲状腺ホルモン","subitem_subject_scheme":"Other"},{"subitem_subject":"遺伝子マーカー","subitem_subject_scheme":"Other"},{"subitem_subject":"メカニカルストレス","subitem_subject_scheme":"Other"},{"subitem_subject":"破骨細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"骨形成因子","subitem_subject_scheme":"Other"},{"subitem_subject":"骨組織リモデリング","subitem_subject_scheme":"Other"},{"subitem_subject":"LDL-Receptor Related Proteins","subitem_subject_scheme":"Other"},{"subitem_subject":"SOST Protein","subitem_subject_scheme":"Other"},{"subitem_subject":"LDL-Receptor Related Protein 4","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"【骨リモデリングの制御機構】 第9章 スクレロスチンによる骨リモデリング制御","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"【骨リモデリングの制御機構】 第9章 スクレロスチンによる骨リモデリング制御"}]},"item_type_id":"10001","owner":"3","path":["268","371","378"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-03-07"},"publish_date":"2018-03-07","publish_status":"0","recid":"2694","relation_version_is_last":true,"title":["【骨リモデリングの制御機構】 第9章 スクレロスチンによる骨リモデリング制御"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-19T08:01:35.781121+00:00"}