{"created":"2023-06-19T07:39:07.783933+00:00","id":2787,"links":{},"metadata":{"_buckets":{"deposit":"813c58da-ea1e-432e-a716-444823ccf211"},"_deposit":{"created_by":3,"id":"2787","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2787"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00002787","sets":["178:204","193:201:202","193:208:298","193:232:265","193:233:297"]},"author_link":["4612","4606","4614","4602","4607","4608","4610","4603","4604","4611","4601","4605","4613","4600","4615","4609"],"item_10001_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Immunohistochemical observations of Heat Shock Ptoteins expression in mouse periodontal tissues due to orthodontic mechanical stress"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"197","bibliographicPageStart":"193","bibliographicVolumeNumber":"18","bibliographic_titles":[{},{"bibliographic_title":"Journal of Hard Tissue Biology","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Muraoka, Rina"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakano, Keisuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsuda, Hirokazu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tomoda, Maki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okafuji, Norimasa"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kurihara, Saburo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamada, Kazuhiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawakami, Toshiyuki"}],"nameIdentifiers":[{}]}]},"item_10001_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"熱ショックタンパク質(HSPs)は熱ショックのみならず、メカニカルストレスに対しても発現する。歯科矯正治療は、関連する歯周組織にメカニカルストレスを付加する。それを受けた後の歯周組織に発現するHSPの状況を調べる事は極めて重要である。そこで今回、我々は歯科矯正学的メカニカルストレスをWaldo法によってddYマウスの歯根膜組織に与え、その後の変化を病理組織学的ならびに免疫組織化学的に検索した。その結果、対象群ではHSP27と70はともに極めて弱い発現であったのに対し、実験群の牽引側歯根膜組織にHSP27と70の両者の発現増強がみられた。これらの所見は、HSPsは歯根膜組織の恒常性の維持に寄与している事を示唆していた。","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Society for Hard Tissue Regenerative Biology (硬組織再生生物学会)"}]},"item_10001_relation_12":{"attribute_name":"NII論文ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"130004480485","subitem_relation_type_select":"NAID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"info:doi/10.2485/jhtb.18.193"}],"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2485/jhtb.18.193","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"雑誌掲載論文(電子版) "}]}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Jstage"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2485/jhtb.18.193","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_24":{"attribute_name":"医中誌ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"2010141791","subitem_relation_type_select":"ICHUSHI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2009 by The Hard Tissue Biology Network Association(JHTBNet) "}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11074332","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-7649","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_25":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_text_value":"Heat shock proteins (HSPs) are induced by not only the heat shock but also the mechanical stress. Orthodontic tooth movement induced mechanical stress in the related periodontal ligament. It is important to examine the inununohistochemical profile change of the Heat shock proteins (HSPs) in the periodontal ligament cells after receiving the mechanical stress for orthodontic treatment. Therefore, we examined the HSPs in the periodontal ligament cells of ddY mice using the Waldo method. In the control group, periodontal ligament was observed as physiological anangement, and which reacted weakly to HSP27 and HSP70. In the experimental group the extension site of the periodontal ligament cells and the expansion of the blood vessel occuned in the traction side. These tissues were strongly reacted to HSP27 and HSP70. The findings suggeste that the HSPsexpression work as the mechanism of maintenance of homeostasis in the periodontal tissues."}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"村岡, 理奈"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"中野, 敬介"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"松田, 浩和"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"共田, 真紀"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岡藤, 範正"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"栗原, 三郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山田, 一尋"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"川上, 敏行"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-02-20"}],"displaytype":"detail","filename":"2018-ja-004.pdf","filesize":[{"value":"310.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"本文","url":"https://mdu.repo.nii.ac.jp/record/2787/files/2018-ja-004.pdf"},"version_id":"3d9911b2-f306-4009-95d8-75f5f5987771"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"メカニカルストレス","subitem_subject_scheme":"Other"},{"subitem_subject":"骨芽細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"歯科矯正","subitem_subject_scheme":"Other"},{"subitem_subject":"歯周組織(病理学)","subitem_subject_scheme":"Other"},{"subitem_subject":"線維芽細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"免疫組織化学","subitem_subject_scheme":"Other"},{"subitem_subject":"HSP70 Heat-Shock Proteins","subitem_subject_scheme":"Other"},{"subitem_subject":"HSP27 Heat-Shock Proteins","subitem_subject_scheme":"Other"},{"subitem_subject":"マウス","subitem_subject_scheme":"Other"},{"subitem_subject":"動物","subitem_subject_scheme":"Other"},{"subitem_subject":"オス","subitem_subject_scheme":"Other"},{"subitem_subject":"歯学","subitem_subject_scheme":"Other"},{"subitem_subject":"Heat Shock Protein","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"HSP27","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"HSP70","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Periodontal ligament cells","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Mechanical stress","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Orthodontic tooth movement","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"歯科矯正学的メカニカルストレスによりマウス歯根膜組織に発現する熱ショックタンパクの免疫組織化学的観察","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"歯科矯正学的メカニカルストレスによりマウス歯根膜組織に発現する熱ショックタンパクの免疫組織化学的観察"}]},"item_type_id":"10001","owner":"3","path":["202","204","265","297","298"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-02-20"},"publish_date":"2019-02-20","publish_status":"0","recid":"2787","relation_version_is_last":true,"title":["歯科矯正学的メカニカルストレスによりマウス歯根膜組織に発現する熱ショックタンパクの免疫組織化学的観察"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-19T07:56:21.834590+00:00"}