{"created":"2023-06-19T07:39:07.985044+00:00","id":2790,"links":{},"metadata":{"_buckets":{"deposit":"79d3c657-efa4-464c-8f80-a00fd9b996ae"},"_deposit":{"created_by":3,"id":"2790","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2790"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00002790","sets":["178:204","193:206:251"]},"author_link":["4626"],"item_10001_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"骨細胞の形態、機能及び分化"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"22","bibliographicPageStart":"15","bibliographicVolumeNumber":"16","bibliographic_titles":[{},{"bibliographic_title":"Journal of Hard Tissue Biology","bibliographic_titleLang":"en"}]}]},"item_10001_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Bone plays a pivotal role in storing calcium and phosphate in vertebrates. This tissue is maintained by the balance of bone formation and bone resorption. Osteoblast-lineage cells, consisting of osteoblasts, osteocytes and bone lining cells, are engaged in bone formation. Bone resorption is mediated by osteoclasts. Recent research revealed that receptor activator of NF-κB (RANK)-RANK ligand (RANKL) mechanism is essential for the differentiating and activating osteoclasts. Osteoblast-lineage cells regulate bone resorption via the expression of RANKL and osteoprotegerin (OPG), a decoy receptor for RANKL. Additionally, osteoblast-lineage cells participate in degradation of bone matrix by secreting MMP-13. Thus, bone remodeling is achieved by the harmonized orchestration of osteoblast-lineage cells and osteoclast-lineage cells. ","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Society for Hard Tissue Regenerative Biology (硬組織再生生物学会)"}]},"item_10001_relation_12":{"attribute_name":"NII論文ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"130004480453","subitem_relation_type_select":"NAID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"info:doi/10.2485/jhtb.16.15"}],"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2485/jhtb.16.15","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"雑誌掲載論文(電子版) "}]}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Jstage"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2485/jhtb.16.15","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_24":{"attribute_name":"医中誌ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"2007329822","subitem_relation_type_select":"ICHUSHI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2007 by The Hard Tissue Biology Network Association(JHTBNet) "}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11074332","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-7649","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakamura, Hiroaki"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-02-20"}],"displaytype":"detail","filename":"2018-ja-009.pdf","filesize":[{"value":"2.8 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"本文","url":"https://mdu.repo.nii.ac.jp/record/2790/files/2018-ja-009.pdf"},"version_id":"c66a0d88-6295-4cdc-87e8-a43a83753046"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"NF-Kappa B","subitem_subject_scheme":"Other"},{"subitem_subject":"遺伝子発現調節","subitem_subject_scheme":"Other"},{"subitem_subject":"骨芽細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"骨基質","subitem_subject_scheme":"Other"},{"subitem_subject":"骨形成","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞間コミュニケーション","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞分化","subitem_subject_scheme":"Other"},{"subitem_subject":"破骨細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"骨組織リモデリング","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞系譜","subitem_subject_scheme":"Other"},{"subitem_subject":"破骨細胞形成抑制因子","subitem_subject_scheme":"Other"},{"subitem_subject":"破骨細胞分化因子","subitem_subject_scheme":"Other"},{"subitem_subject":"Matrix Metalloproteinase 13","subitem_subject_scheme":"Other"},{"subitem_subject":"Bone","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Cell-cell interaction","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Osteoblasts","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Osteoclasts","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Morphology, Function, and Differentiation of Bone Cells","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Morphology, Function, and Differentiation of Bone Cells","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"3","path":["204","251"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-02-20"},"publish_date":"2019-02-20","publish_status":"0","recid":"2790","relation_version_is_last":true,"title":["Morphology, Function, and Differentiation of Bone Cells"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-19T07:55:26.898409+00:00"}