{"created":"2023-06-19T07:39:11.510680+00:00","id":2863,"links":{},"metadata":{"_buckets":{"deposit":"36c2cd6d-f1d6-4f78-b9e3-ae2488af86ae"},"_deposit":{"created_by":3,"id":"2863","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2863"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00002863","sets":["170:500"]},"author_link":["4921","4928","4925","4922","4924","4930","4927","4919","4929","4920","4926","4923"],"item_10_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Effects of nitrous oxide sedation on sympathetic batireflex 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Sympathetic Nerve Activity：MSNA）を同時測定し，動脈圧の変動に対する末梢血管調節性交感神経活動の変化量からBRSを検証した．健常成人男性10名［31±2歳］を対象に，水平仰臥位でルームエアー，100％酸素（O2），30％N2O，40％N2Oをそれぞれ20分間吸入した後，各条件下で心拍数（HR），心拍出量（CO），1回拍出量（SV），連続血圧およびMSNAを5分間測定した．さらに，O2を20分間吸入した後に回復期を設け，ルームエアーで5分間同様の測定をした．BRSの評価のために，まず，連続血圧の拡張期血圧（DBP）を3mmHgごとにグルーピングを行い，各グループのDBP平均値をDBPの代表値とし，100拍あたりのMSNAのバースト数（BI）とバースト面積（Total MSNA）をMSNA代表値とした．各グループのDBPとBIおよびTotal MSNA代表値から求めた直線回帰の傾きを交感神経性圧受容器反射感受性（sBRS）とした．各IS条件間でHR，CO，血圧に差はなかった．また，DBPとBIおよびTotal MSNAで求めたsBRSは両者ともIS濃度による変動を示さなかった．以上から，笑気吸入中に圧受容器反射のオペレーティングポイント，感受性とも維持されることが示唆された．","subitem_description_type":"Abstract"}]},"item_10_dissertation_number_23":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"乙第32号"}]},"item_10_relation_13":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"J-Stage"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.14958/jjsdh.39.395","subitem_relation_type_select":"DOI"}}]},"item_10_relation_16":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.14958/jjsdh.39.395","subitem_relation_type_select":"DOI"}}]},"item_10_relation_9":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"雑誌掲載論文"}]}]},"item_10_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2018 一般社団法人 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