@article{oai:mdu.repo.nii.ac.jp:00002889,
 author = {KAWAHARA, ICHIRO and TSUJIMOTO, MAKOTO and MURAKAMI, GOUICHI and SADAOKA, SUNAO and KAWAHARA, YOSHIMI and 川原, 一郎 and 辻本, 真 and 村上, 剛一 and 定岡, 直 and 川原, 良美},
 issue = {2},
 journal = {松本歯学, Journal of the Matsumoto Dental University Society},
 month = {Dec},
 note = {application/pdf, Even today, pH measurement of living tissue in a clinical environment has been difficult. In this study, we succeeded in measuring the pH of　living tissue and observing changes over time using an optical fiber coated with a newly developed pH–reactive fluorescent substance. A standardized hole was made in the rat tibia, Poly Ether Ether Ketone (PEEK) and Commercially₇ days.  As a result, it was confirmed that the pH of the tissue was increased with CP–tita-nium, in which osseointegration was confirmed, and with PEEK, which imparted surface wettability.  In addition, a decrease in pH over time due to tissue damage was also confirmed.  From the above, it was confirmed that a needle–type pH microsensor is suitable for measuring the pH of living tissue over time.  With this method, the development of new implant materials can be expected. Pure (CP)–titanium were implanted, and the pH change was measured after},
 pages = {97--102},
 title = {生体における微小領域組織のpH測定ーニードル型pHマイクロセンサー応用の報告},
 volume = {45},
 year = {2019}
}