{"created":"2023-06-19T07:37:20.705698+00:00","id":365,"links":{},"metadata":{"_buckets":{"deposit":"53058412-d4b9-49e5-81da-97423c356436"},"_deposit":{"created_by":3,"id":"365","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"365"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00000365","sets":["1:52:64"]},"author_link":["0"],"item_2_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Bacteriocins, Antimicrobial Substances from Oral Bacteria and Ecosystem of the Flora"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1983-12-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"150","bibliographicPageStart":"135","bibliographicVolumeNumber":"9","bibliographic_titles":[{"bibliographic_title":"松本歯学"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Causative agents of oral infectious diseases are normal residents in the oral cavity. From the point of view that one of the conceivable factors which controls the ecosystem of normal flora is bacteriocin (or a bacteriocin-like substance), we have studied biological properties of some bacteriocins elaborated by the members of indigenous oral bacteria. Author report here an outline of the properties of several bacteriocins. (i) Bacteriocins of dental plaque bacteria Strains of St. sanguis, P. acnes, and B. matruchotii which produced bacteriocins, were isolated from dental plaque. M. W. of a bacteriocin from St. sanguis was 280,000. It inhibited the growth of Bacterodes, P. acnes, and Actinomyces bacteriostatically. A bacteriocin from P. acnes composed of five subunits. M. W. of the native from was 60,000. It's inhibitory spectrum was very narrow. B. matruchotii produced an extracellular bacteriocin by shaking cultivation. This purified bacteriocin contained two components. However, there was no significant difference in the inhibitory spectrum between the two components. (ii) Bacteriocin of gingival crevice bacteria About a half of B. melaninogenictis strains isolated from gingival crevice deposits exhibited antibacterial activity and the bacteriocin was obtained from cell extract of this organism. The purified bacteriocin was 105,000 in M. W. and inhibited the growth of Bacteroides, Actinomyces, St. mitis, and St. salivarius. It was also revealed that hematin accumulated within the cells of this organism was able to inhibit many gram positive bacteria including St. mutans. (iii) Bacteriocin of saliva bacteria In the culture supernatant of S. aureus obtained from saliva, a relatively low M. W. (6,000) bacteriocin was found It was basic polypeptide with a pi value of 10.0, and a high content of lysine was characteristic. This bacteriocin killed St. salivarius, P. acnes, A. israelii, and nonbacteriocinogenic 5. aureus. On the basis of this information, the possible ecological role of the bacteriocins or bacteriocin-like substances in oral microorganisms on the flora is discussed.","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"松本歯科大学学会"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00232590","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-1613","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中村, 武"}],"nameIdentifiers":[{"nameIdentifier":"0","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2012-05-23"}],"displaytype":"detail","filename":"matsumoto_shigaku_09-02-01.pdf","filesize":[{"value":"1.7 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"matsumoto_shigaku_09-02-01.pdf","url":"https://mdu.repo.nii.ac.jp/record/365/files/matsumoto_shigaku_09-02-01.pdf"},"version_id":"db6c328c-7c15-4079-bfeb-d090b13b5f61"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Bacteriocins","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Antimicrobial agents","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Ecosystem","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Oral flora","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"抗菌物質産生の口腔細菌とその生態","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"抗菌物質産生の口腔細菌とその生態"}]},"item_type_id":"2","owner":"3","path":["64"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-05-23"},"publish_date":"2012-05-23","publish_status":"0","recid":"365","relation_version_is_last":true,"title":["抗菌物質産生の口腔細菌とその生態"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T08:39:45.226981+00:00"}