{"created":"2023-06-19T07:37:02.094466+00:00","id":38,"links":{},"metadata":{"_buckets":{"deposit":"02712ce6-d4fb-48c0-9c7e-d59ce87554c1"},"_deposit":{"created_by":16,"id":"38","owners":[16],"pid":{"revision_id":0,"type":"depid","value":"38"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00000038","sets":["1:4:5"]},"author_link":["0"],"item_2_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Biological Activity of Endotoxin from Oral Heparinase-producing Bacteroides"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1976-06-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"19","bibliographicPageStart":"12","bibliographicVolumeNumber":"2","bibliographic_titles":[{"bibliographic_title":"松本歯学"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A possible role of oral Heparinase-producing Bacteroides which resembles to Bacteroides oralis in the character in the etiology of periodontal disease has been emphasized by the authors. This is mainly based on the facts that they possessed heparinase and remarkably increase in number in the local samples of experimental mixed infection by human dental plaque following serial transfer. The present study dealed with the extraction and characterization of the endotoxin from the cells of the Bacteroides. Three strains which differed from each other in the heparinase activity were grown in Trypticase broth for 5 days anaerobically at 37℃. Harvested cells were washed three times with acetone, dried under CaCl_2 and subjected to extraction. Endotoxin were extracted by phenol-water (1:1) according to Westphal method with some modifications. The recoveries of preparation were 7～17% by dry weight basis. Preparations were whitish powder and water-soluble. Preparations pyrogenicity, Shwartzman reactive activity and cytotoxic activity of the endotoxin were demonstrated. The higher endotoxic activity was observed in the preparation with higher recovery. In the Shwartzman reaction, a positive correlation was found between preparatory activity of the endotoxin and the heparinase activity of the strain.","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"松本歯科大学学会"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00232590","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-1613","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中村, 武"},{"creatorName":"杉中, 芳幸"},{"creatorName":"高添, 一郎"},{"creatorName":"奥田, 克爾"}],"nameIdentifiers":[{"nameIdentifier":"0","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2012-04-27"}],"displaytype":"detail","filename":"matsumoto_shigaku_02-01-02.pdf","filesize":[{"value":"749.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"matsumoto_shigaku_02-01-02.pdf","url":"https://mdu.repo.nii.ac.jp/record/38/files/matsumoto_shigaku_02-01-02.pdf"},"version_id":"2fbab843-2645-472b-a861-f61fb496a489"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"口腔内Heparinase産生性BacteroidesのEndotoxinの生物学的活性","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"口腔内Heparinase産生性BacteroidesのEndotoxinの生物学的活性"}]},"item_type_id":"2","owner":"16","path":["5"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-04-27"},"publish_date":"2012-04-27","publish_status":"0","recid":"38","relation_version_is_last":true,"title":["口腔内Heparinase産生性BacteroidesのEndotoxinの生物学的活性"],"weko_creator_id":"16","weko_shared_id":-1},"updated":"2023-06-19T08:46:58.698748+00:00"}