@article{oai:mdu.repo.nii.ac.jp:00000445,
 author = {安東, 孝治 and 石和田, 敏貴 and 森山, 敬太 and 影山, 康子 and 影山, 徹 and 佐原, 紀行},
 issue = {2},
 journal = {松本歯学},
 month = {Apr},
 note = {application/pdf, This study investigated the effects of age on histological changes in periodontal tissues surrounding occlusal hypofunctional molars in rats. Rats (n=60) of 3 different age groups, i. e., 10-, 50-, and 80-wk-old animals, were used for the experiment. To eliminate occlusal force on the mandibular first molars, the maxillary first molar crowns were resected below their gingival margins. Thirty age-matched untreated rats were used as control groups. Ten days after operation, the animals were sacrificed, and histological changes in the periodontal tissues, such as cementum, alveolar bone, and periodontal membrane, were investigated. In all aged rats, there were rapid atrophic changes in the periodontal membrane, and new bone formation on the alveolar surface narrowed the periodontal space to about half that of age-matched control animals. Fluorescent labeling demonstrated that woven-bone formation was noted at the top of the interradicular septa and at the bottom of the sockets. However, the amount of bone formation of the alveolar bone surface decreased with age . The results of the present study demonstrate that histological changes of the periodontal tissues surrounding rat molars after experimental hypofunction differ in degree but not in kind between the different experimental age groups, and suggest that the degree of histological changes is age-dependent and decreases with age.},
 pages = {172--186},
 title = {咬合圧除去による歯周組織の変化：特に加齢による比較},
 volume = {33},
 year = {2007}
}