@article{oai:mdu.repo.nii.ac.jp:00000515,
 author = {中村, 浩彰},
 issue = {2},
 journal = {松本歯学},
 month = {Aug},
 note = {application/pdf, Bone is an actively metabolized tissue. Bone volume is maintained through a balance of bone formation by osteoblasts and bone resorption by osteoclasts. Recent research demon-strated that receptor activator of NF-kB (RANK)-RANK ligand (RANKL) mechanism plays a pivotal role in the differentiating and activating osteoclasts. Osteoblast-lineage cells, consisting of osteoblasts, osteocytes and bone lining cells, regulate bone resorption via the expression of RANKL. The balance of RANKL and OPG, a decoy receptor for RANKL, is thought to regulate the bone remodeling. Thus, bone remodeling is accomplished by the harmonized interaction between osteoblast-lineage cells and osteoclasts. RANK-RANKL mechanism is also engaged in pathological bone resorption such as periodontal diseases. New approach based on the interaction between osteoblasts and osteoclasts will be neces-sary to prevent and treat bone diseases.},
 pages = {131--137},
 title = {骨代謝における骨芽細胞と破骨細胞の細胞連関},
 volume = {31},
 year = {2005}
}