{"created":"2023-06-19T07:37:37.674981+00:00","id":640,"links":{},"metadata":{"_buckets":{"deposit":"43c716b3-3415-4c61-a16a-272d74b8262d"},"_deposit":{"created_by":3,"id":"640","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"640"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00000640","sets":["1:35:110"]},"author_link":["0"],"item_2_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"The Correlation between Osteoporosis and Periodontal Disease"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2001-12-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2-3","bibliographicPageEnd":"87","bibliographicPageStart":"77","bibliographicVolumeNumber":"27","bibliographic_titles":[{"bibliographic_title":"松本歯学"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Osteoporosis and periodontal disease are both major health problems among the elderly. The etiology and risk factors of both diseases are multifactorial and similar. Osteoporosis has been suggested as a contributing etiologic factor because it is known to cause a generalized skeletal decrease in bone mass. The purpose of our study was to investigate the effect of decreasing hormone secretion which changes alveolar bone loss and clinical parameters in pre versus post menopausal female periodontal disease patients. We determined the correlation between periodontal disease and osteoporosis compared with alveolar bone loss calculated by dental X-ray film, panoramic radiographic parameters and various clinical parameters of the disease. The diagnosis of osteoporosis in periodontal disease patients was also evaluated by panoramic radiographic parameters. Adult female subjects were examined without systemic disease, treatment of periodontal disease, or juvenile periodontitis or occlusal traumatism. They were classified into premenopausal group and post-menopausal group. Adult male periodontal disease patients were examined as a control group. Each subject had more than 20 teeth and was examined by dental X-ray film and panoramic radiography. Subjects were stratified into 10 year spans (from 20 to 70 years). The post menopausal group was subdivided into; 1-5, 6-10, and>11 years post-menopausal groups. Clinical parameters (number of teeth present except third molars, plaque control record, probing pocket depth, gingival index, gingival bleeding index, mobility, clinical attachment level (CAL)) and the amount of alveolar bone loss by dental X-ray film were examined. The following parameters were examined on panoramic X-ray film: alveolar bone loss (ABL), mandibular bone mass with the use of mandibular cortical width (MCW) and Centric panoramic mandibular index (C-PMI). In each group, subjects were compared for the amount of alveolar bone loss, panoramic parameters and clinical parameters. We also analyzed the correlations between these parameters. The diagnosis of osteoporosis was determined by MCW. The results indicated that the amount of alveolar bone loss in each post menopausal group to be significantly larger than in the pre menopausal group. Age and ABL in male and female groups, and years after menopause and ABL were correlated positively. Anterior teeth in the post menopausal groups showed larger amounts of alveolar bone loss than in the pre menopausal group. The amount of alveolar bone loss in the post menopausal group exceeded that in male control groups of the same age. There were no significant differences between male and female groups except for MCW. MCW was significantly lower in the postmenopausal group (>6 years after menopause). CAL was significantly lower in the postmenopausal group (>11 years after menopause). MCW and ABL in postmenopausal groups and MCW and CAL in postmenopausal groups were correlated positively. Two female subjects whose MCW was less than the mean value 2 SD, were diagnosed with osteoporosis. These results suggest increased alveolar bone loss changes in the menopausal stage, in response to decreased hormone secretion. Our studies demonstrated that periodontal disease correlates with osteoporosis and MCW could be useful for the detection of osteoporosis in female periodontal disease patients. Following these clinical studies, we investigated the effects of osteoporosis on alveolar bone loss in 4 and 8-week-old female rats. We divided then into four groups, ovariectomized or not, and they were fed a standard diet or a calcium deficient diet. After 1, 4, 16, 52 week periods, alveolar bone loss was calculated. These results showed that the bone mineral density of mandibular bone in ovariectomized rats was not significantly higher than in ovariectomized rats and osteoporosis itself may not be capable of causing alveolar bone destruction. Guided bone regeneration (GBR) has been widely utilized for the promotion of bone augmentation in bone loss areas. We examined the effects of the GBR technique with resorbtion on bone cavities at the mandibular angle in osteoporosis rats. The newly formed bone was evaluated histologically and statistically. These results suggested the GBR could be an useful technique for bone defects in osteoporosis patients.","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"松本歯科大学学会"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00232590","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-1613","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"音琴, 淳一"},{"creatorName":"太田, 紀雄"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2012-05-24"}],"displaytype":"detail","filename":"matsumoto_shigaku_27-02-01.pdf","filesize":[{"value":"884.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"matsumoto_shigaku_27-02-01.pdf","url":"https://mdu.repo.nii.ac.jp/record/640/files/matsumoto_shigaku_27-02-01.pdf"},"version_id":"8af454d7-8a5d-45dd-a1cb-a275f53e2690"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"歯周疾患罹患患者","subitem_subject_scheme":"Other"},{"subitem_subject":"閉径","subitem_subject_scheme":"Other"},{"subitem_subject":"骨粗髪症","subitem_subject_scheme":"Other"},{"subitem_subject":"X線写真パラメーター","subitem_subject_scheme":"Other"},{"subitem_subject":"臨床パラメーター","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"歯周疾患と全身疾患の関わり : 骨粗鬆症との関連を探る","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"歯周疾患と全身疾患の関わり : 骨粗鬆症との関連を探る"}]},"item_type_id":"2","owner":"3","path":["110"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-05-24"},"publish_date":"2012-05-24","publish_status":"0","recid":"640","relation_version_is_last":true,"title":["歯周疾患と全身疾患の関わり : 骨粗鬆症との関連を探る"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T08:33:25.518160+00:00"}