{"created":"2023-06-19T07:37:39.221059+00:00","id":664,"links":{},"metadata":{"_buckets":{"deposit":"bb7aa4ae-8655-49f2-9883-0c7d03b61884"},"_deposit":{"created_by":3,"id":"664","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"664"},"status":"published"},"_oai":{"id":"oai:mdu.repo.nii.ac.jp:00000664","sets":["1:36:108"]},"author_link":["0"],"item_2_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"有害金属拮抗薬DMSAおよびDMPSのヒ酸ナトリウムの排泄に対する作用"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2000-12-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2-3","bibliographicPageEnd":"105","bibliographicPageStart":"102","bibliographicVolumeNumber":"26","bibliographic_titles":[{"bibliographic_title":"松本歯学"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Previous studies have shown that DMSA (meso-2, 3-dimercaptosuccinic acid, succimer) and DMPS (2, 3-dimercapto-1-propane sulfonic acid, Na salt, unithiol) are effective antidotes for pentavalent arsenate and trivalent arsenite because they reduce the mortality of mice poisoned with these arsenic compounds. Studies have also shown that in mice treated with arsenite, DMPS and DMSA promote excretion of arsenic into the bile and urine, respectively. This study was conducted to determine whether DMSA and DMPS promote arsenate excretion to the same extent as previously reported for arsenite. The results demon-strated that DMPS antagonized arsenate toxicity by improving excretion of arsenic, although to a lesser extent than in studies with arsenite, while DMSA showed a slight but statistically insignificant promotion of early arsenic excretion in the urine.","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"松本歯科大学学会"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00232590","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-1613","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"MIYAZAZWA, TOSHIKO"},{"creatorName":"NAITO, MAKOTO"},{"creatorName":"MAEHASHI, HIROSHI"}],"nameIdentifiers":[{"nameIdentifier":"0","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2012-05-24"}],"displaytype":"detail","filename":"matsumoto_shigaku_26-02-02.pdf","filesize":[{"value":"247.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"matsumoto_shigaku_26-02-02.pdf","url":"https://mdu.repo.nii.ac.jp/record/664/files/matsumoto_shigaku_26-02-02.pdf"},"version_id":"308d3d4d-40aa-4ccb-858d-dd32941d8d91"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"DMSA","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"DMPS","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Arsenate excretion","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Mice","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The Effects of DMSA and DMPS on Arsenate Excretion in Mice","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The Effects of DMSA and DMPS on Arsenate Excretion in Mice","subitem_title_language":"en"}]},"item_type_id":"2","owner":"3","path":["108"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-05-24"},"publish_date":"2012-05-24","publish_status":"0","recid":"664","relation_version_is_last":true,"title":["The Effects of DMSA and DMPS on Arsenate Excretion in Mice"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T08:32:49.330512+00:00"}