@article{oai:mdu.repo.nii.ac.jp:00000670, author = {織田, 秀樹 and 澁谷, 徹 and 谷山, 貴一 and 土佐, 亜希子 and 廣瀬, 伊佐夫 and 高井, 経之 and 小笠原, 正 and 笠原, 浩}, issue = {2-3}, journal = {松本歯学}, month = {Dec}, note = {application/pdf, We present a 5-year-old boy with late infantile form of Krabbe disease who required general anesthesia for dental treatment. He was diagnosed with Krabbe disease at 1 year and 6 months old, and bone marrow transplantation was performed to prevent the neurological deterioration at 2 years old. He presented severe neurodegeneration and quadriplegia, and could not move actively except for tossing about from laterel to supine position. A diazepam syrup (2 mg) was administered 90 minutes before the start of anesthesia. After the establishment of a venous route, anesthesia was induced with thiopental sodium (50 mg), and nasotracheal intubation was facilitated with vecuronium bromide (1.4 mg). The anesthesia was maintained with N_2O (3.0l/min), O_2 (1.5l/min) and sevoflurane (1.0~2.0%). Pulpectomy and dental prosthesis for every 20 deciduous teeth was performed, and the anesthesia was completed uneventfully after 5 hours and 50 minutes.}, pages = {133--136}, title = {Krabbe病患者の全身麻酔経験}, volume = {26}, year = {2000} }