@article{oai:mdu.repo.nii.ac.jp:00000719,
 author = {芦澤, 雄二 and 岸本, 雅吉 and 中村, 康洋 and 岡藤, 範正 and 出口, 敏雄 and 長谷川, 亨 and 佐原, 紀行 and 鈴木, 和夫},
 issue = {3},
 journal = {松本歯学},
 month = {Dec},
 note = {application/pdf, Using a single injection for lead vital staining, we observed dynamic events of bone remodeling activity of the alveolar bone incidental to experimental tooth movement. Rat maxillary first molars were moved mesially, with a coil-spring appliance for 7 days. EDTA-Pb as intraperitoneally injected 3 hours before sacrifice. The animals were euthanized 3, 6, 12, 24, 48, 72 hours and 7 days after tooth movement. Lead deposition lines on the alveolar surface surrounding the roots were examined. Furthermore, histological changes after tooth movement were examined regarding the morphological alternations of osteoblasts on the alveolar surface. Non-treated rats were used as controls. In controls, only 1 lead deposition line as clearly identified on the whole alveolar bone surface encircling the root. However, on the mesial/pressure side in experimental groups after 12 hours of mesial movement, lead deposition could not be found in any area on the alveolar bone surface, demonstrating that the bone formation activity began to disappear from this area due to tooth movement. Changes in the lead deposition line on the alveolar bone surface on the pressure side, closely corresponded to morphological alternations of osteoblasts on the alveolar bone surface after tooth movement. These results suggest that this lead vital staining technique can visualize bone formation activity on the alveolar surface surrounding the roots, and is an useful method to observe dynamic events of bone remodeling activity of the alveolar bone, incidental to experimental tooth movement.},
 pages = {252--261},
 title = {実験的歯の移動に伴う歯槽骨骨改造活性の動的把握の試み : 鉛生体染色法を用いて},
 volume = {24},
 year = {1998}
}