@article{oai:mdu.repo.nii.ac.jp:00000730, author = {長谷川, 亨 and 大口, 弘和 and 佐原, 紀行 and 鈴木, 和夫}, issue = {2}, journal = {松本歯学}, month = {Aug}, note = {application/pdf, Using anti-human mast cell tryptase antibodies, immunohistochemical examinations of mast cells were performed on 10 clinically healthy and 10 chronically inflamed human gingival specimens. The clinically healthy gingiva was found to be rich in mast cells. Immunostaining revealed about 200 mast cells per mm^2, and about 150 metachromatic cells per mm^2. A significant difference in mast cell numbers between both techniques was found within the pocket area. Many mast cells were also found in the chronically inflamed gingival specimens, however, the number of mast cells showed extensive individual variations. The results demonstrate that the immunostaining technique presently used is a specific and reliable method to examine of mast cells in human gingiva. Individual variations in mast cell density of chronically inflamed gingival specimens may be due to differences in degree, type and period of irritation, however, extended studies with larger samples are needed to provide additional information regarding on the role of the mast cells in gingival inflammation.}, pages = {198--205}, title = {ヒト歯肉組織の肥満細胞免疫組織化学的研究}, volume = {24}, year = {1998} }