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顎顔面領域における炎症モデルラット三叉神経節細胞の遺伝子発現動態 : カルモジュリンキナーゼとK+チャネルの解析
https://mdu.repo.nii.ac.jp/records/426
https://mdu.repo.nii.ac.jp/records/42638c67278-5e8d-4e78-b87e-62c462115232
名前 / ファイル | ライセンス | アクション |
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matsumoto_shigaku_33-03-02.pdf (791.6 kB)
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Item type | Journal Article(1) | |||||
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公開日 | 2012-05-24 | |||||
タイトル | ||||||
タイトル | 顎顔面領域における炎症モデルラット三叉神経節細胞の遺伝子発現動態 : カルモジュリンキナーゼとK+チャネルの解析 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 三叉神経節 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 炎症 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 遺伝子動態 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | イオンチャンネル | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | セカンドメッセンジャー | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
その他(別言語等)のタイトル | ||||||
その他のタイトル | Gene expression patterns in the rat trigeminal ganglion neurons under orofacial inflammation : Calcium/calmodulin-dependent protein kinase II and potassium ion channel | |||||
著者 |
姫野, 勝仁
× 姫野, 勝仁 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | This study investigated functions of the K^+ channel family K member3 (KCNK3) and Calmodulin kinase II β (CaMK II β) in rat trigeminal ganglion neurons under orofacial inflammation. We investigated gene expression following orofacial inflammation in the rat trigeminal ganglion using complementary DNA microarray. Up-regulation of two molecule genes, KCNK3 and CaMK II β mRNAs were demonstrated. Therefore, we investigated the two molecules showing changes in gene expression, pattern and quantity over a 1-week time course after injection of Complete Freund's Adjuvant (CFA) to the rat upper lip. Trigeminal ganglion neurons, 3 days after CFA injection, expressed the two molecule mRNAs and strong staining was identified ipsilateral to the injection site by in situ hybridization histo-chemistry. Quantity of KCNK3 mRNA participated in the changes during orofacial inflammation. These data suggest that profound mechanisms are involved in the symptom. | |||||
書誌情報 |
松本歯学 巻 33, 号 3, p. 269-275, 発行日 2007-12-31 |
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出版者 | ||||||
出版者 | 松本歯科大学学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0385-1613 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00232590 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |