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骨代謝における骨芽細胞と破骨細胞の細胞連関
https://mdu.repo.nii.ac.jp/records/515
https://mdu.repo.nii.ac.jp/records/515d3fab1a2-7d63-420b-b0bf-9fdc9da169bf
名前 / ファイル | ライセンス | アクション |
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matsumoto_shigaku_31-02-01.pdf (2.1 MB)
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Item type | Journal Article(1) | |||||
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公開日 | 2012-05-24 | |||||
タイトル | ||||||
タイトル | 骨代謝における骨芽細胞と破骨細胞の細胞連関 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Osteoblasts | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Osteoclsts | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | RANKL | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | OPG | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | MMP 13 | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
その他(別言語等)のタイトル | ||||||
その他のタイトル | Cell-Cell Interaction between Osteoblast-lineage Cells and Osteoclasts | |||||
著者 |
中村, 浩彰
× 中村, 浩彰 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Bone is an actively metabolized tissue. Bone volume is maintained through a balance of bone formation by osteoblasts and bone resorption by osteoclasts. Recent research demon-strated that receptor activator of NF-kB (RANK)-RANK ligand (RANKL) mechanism plays a pivotal role in the differentiating and activating osteoclasts. Osteoblast-lineage cells, consisting of osteoblasts, osteocytes and bone lining cells, regulate bone resorption via the expression of RANKL. The balance of RANKL and OPG, a decoy receptor for RANKL, is thought to regulate the bone remodeling. Thus, bone remodeling is accomplished by the harmonized interaction between osteoblast-lineage cells and osteoclasts. RANK-RANKL mechanism is also engaged in pathological bone resorption such as periodontal diseases. New approach based on the interaction between osteoblasts and osteoclasts will be neces-sary to prevent and treat bone diseases. | |||||
書誌情報 |
松本歯学 巻 31, 号 2, p. 131-137, 発行日 2005-08-31 |
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出版者 | ||||||
出版者 | 松本歯科大学学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0385-1613 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00232590 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |