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ラットの皮下組織内に埋入した根管充塡材中のシリコーン・オイルの動態
https://mdu.repo.nii.ac.jp/records/1149
https://mdu.repo.nii.ac.jp/records/11495a12c8d2-1cf5-418a-a031-a162552afeae
名前 / ファイル | ライセンス | アクション |
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Item type | Journal Article(1) | |||||||
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公開日 | 2012-05-24 | |||||||
タイトル | ||||||||
タイトル | ラットの皮下組織内に埋入した根管充塡材中のシリコーン・オイルの動態 | |||||||
言語 | ||||||||
言語 | jpn | |||||||
キーワード | ||||||||
主題Scheme | Other | |||||||
主題 | シリコーン・オイル | |||||||
キーワード | ||||||||
主題Scheme | Other | |||||||
主題 | 生体内分布 | |||||||
キーワード | ||||||||
主題Scheme | Other | |||||||
主題 | 根管充塡剤(材) | |||||||
キーワード | ||||||||
主題Scheme | Other | |||||||
主題 | 動態 | |||||||
キーワード | ||||||||
主題Scheme | Other | |||||||
主題 | 放射性同位元素 | |||||||
資源タイプ | ||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
資源タイプ | journal article | |||||||
その他(別言語等)のタイトル | ||||||||
その他のタイトル | Fate of the Silicone Oil Component of a Root Canal Filling Material Embedded in Rat Subcutaneous Tissue | |||||||
著者 |
川上, 敏行
× 川上, 敏行
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抄録 | ||||||||
内容記述タイプ | Abstract | |||||||
内容記述 | Using a ^<14>C-labeled compound, the fate of the silicone oil component of the root canal filling material "Vitapex" embedded in subcutaneous tissue was investigated. Under general anesthesia, a total of 500 mg of paste (500 μCi of ^<14>C) was embedded in the dorsal subcutaneous connective tissue of a rat. The animal was kept in a metabolic cage during the experimental period. The feces and urine were collected every day. Thirteen days after embedding, the animal was killed and organs were taken. Radioactivity of the feces, urine, and organs was measured with a liquid scintillation spectrometer. The results are as follows. Some of the ^<14>C compound was excreted in the feces and urine. The amount excreted in the feces averaged 3.1217 × 10^<-2> μCi/day, and the total amount over the experimental period (13 days) was 4.5818 × 10^<-1> μCi. In the urine, the ^<14>C level averaged about 10-fold less, or 3.6646 × 10^<-3> μCi/day, and 4.7640 × 10^<-2> μCi was excreted over the experimental period. The total amount excreted by the animal (in feces and urine) was thus 5.0583 × 10^<-1> μCi, equal to about 0.1% of the total dose (500 μCi) embedded. Further, the ^<14>C-labeled compound was found distributed in many tissues and organs, such as the skin, kidney, bladder, liver, bone, digestive tract, blood, adrenal gland, and spleen. | |||||||
書誌情報 |
松本歯学 巻 15, 号 2, p. 167-172, 発行日 1989-08-31 |
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出版者 | ||||||||
出版者 | 松本歯科大学学会 | |||||||
ISSN | ||||||||
収録物識別子タイプ | ISSN | |||||||
収録物識別子 | 0385-1613 | |||||||
書誌レコードID | ||||||||
収録物識別子タイプ | NCID | |||||||
収録物識別子 | AN00232590 | |||||||
フォーマット | ||||||||
内容記述タイプ | Other | |||||||
内容記述 | application/pdf | |||||||
著者版フラグ | ||||||||
出版タイプ | VoR | |||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |