| Item type |
松本歯学/学術雑誌論文 / Journal Article(1) |
| 公開日 |
2015-12-01 |
| タイトル |
|
|
タイトル |
Experimental model of occlusal trauma in mouse periodontal tissues. |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Occlusal trauma |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Periodontal tissue |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Experimental model |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Mouse |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Histopathology |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| その他（別言語等）のタイトル |
|
|
その他のタイトル |
Occlusal trauma |
| その他（別言語等）のタイトル |
|
|
その他のタイトル |
Periodontal tissue |
| その他（別言語等）のタイトル |
|
|
その他のタイトル |
Experimental model |
| その他（別言語等）のタイトル |
|
|
その他のタイトル |
Mouse |
| その他（別言語等）のタイトル |
|
|
その他のタイトル |
Histopathology |
| 著者 |
Fujii, T
Takaya, T
Mimura, H
Osuga, N
Matsuda, S
Nakano, K
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
The aim of this study was to establish a model, which can be used to investigate the response of periodontal tissues to excessive occlusal loading in mice by observing histopathological changes. The experiment was performed on ten 7-week-old ddY male mice. Under general anesthesia by intraperitoneal injection
pentobarbital sodium, a micro-plus-screwpin (head part, 1.7mm in diameter, thickness 0.5mm thickness) was screwed into the pulp cavity of the upper-left-first molar. R_mCT images of the experimental site indicated the occlusal contact position between the upper- and lower-left-first molars during the experimental periods. A micro-plus-screwpin was maintained at a constant position on the occlusal surface throughout the experimental period. Histopathological changes of the periodontal ligament at the furcation lesion of the lower-left-first molar and its surrounding periodontal tissues were observed under a light microscope. The densities of deeply dyeing cells in hematoxylin staining with a round-shaped nucleus were increased in the periodontal ligament, with a peak effect of day 4. Multinucleated giant cells appeared in the central lesion of the periodontal ligament on day 7. The distribution of resorption on the surface of both of the cementum and the alveolar bone was accompanied by multinucleated giant cells, which expanded rapidly from day 7 to day 14. These results showed that histopathological changes of periodontal tissues to excessive occlusal load were observed at the furcation area of molar teeth. The present method confirmed the effectiveness of the experimental model to examine the occlusal trauma on periodontal tissues produced by excessive occlusal load. |
| 書誌情報 |
en : Journal of Hard Tissue Biology
巻 23,
号 3,
p. 377-380,
発行日 2014-07
|
| 出版者 |
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|
出版者 |
The Hard Tissue Biology Network Association(JHTBNet) |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1341-7649 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11074332 |
| NII論文ID |
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関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
NAID |
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|
関連識別子 |
130004848432 |
| 医中誌ID |
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|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
ICHUSHI |
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|
関連識別子 |
2015175939 |
| DOI |
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|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.2485/jhtb.23.377 |
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|
関連名称 |
info:doi/10.2485/jhtb.23.377 |
| 権利 |
|
|
権利情報 |
Copyright © 2014 Fujii T et al by The Hard Tissue Biology Network Association(JHTBNet) |
| 情報源 |
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|
関連名称 |
雑誌掲載論文(電子版) |
| 関連サイト |
|
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.2485/jhtb.23.377 |
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|
関連名称 |
Jstage |
| フォーマット |
|
|
内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
本文 (981.7 kB)
