| Item type |
図書 / Book(1) |
| 公開日 |
2019-01-28 |
| タイトル |
|
|
タイトル |
Chapter 6 : Bone marrow masenchymal cell contribution in maintenance of periodontal ligament homeostasis. |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
periodontal ligament(PDL) |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
homeostasis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
cell migration |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
bone marrowderived |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
notch signaling |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_2f33 |
|
資源タイプ |
book |
| 著者 |
KAWAKAMI, TOSHIYUKI
KANAKO, KEIKO
TAKAYA, TATSUO
AOKI, SAEKA
MURAOKA, RINA
OKAFUJI, NORIMASA
SHOUMURA, MASAHITO
OSUGA, NAOTO
TSUJIKAWA, HIDETSUGU
NAGATUKA, HITOSHI
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
In general, remodeling phenomenon of the periodontal ligament (PDL) is occurring in all times. Thus, in the chapter, the word “maintenance” was used, and the chapter title is “Maintenance of Periodontal Ligament Homeostasis.” Our experimental data on the remodeling of the PDL with cell acceleration at the furcation area in this experimental model are recovered using the cells in situ and the bone marrow-derived cells (BMCs).BMC migration into the PDL tissues using green Ěuorescent protein (GFP)bone marrow-transplanted model mouse was examined. BMCs have abilities of cell migration and diěerentiation into tissues/organs in the body. The immunohistochemistry revealed that GFP-positive cells were detected in the PDL.GFP-positive cells were also positive to CD31, CD68, and Runx2 suggesting that ębroblasts diěerentiated into osteoclasts and tissue macrophages. In this way, Notch signaling involvement considered in our tentative examinations revealed that the experimentally induced periodontal polyp was examined; the cytological dynamics of the cells in granulation tissue are mainly from migration of undiěerentiated mesenchymal cells of the bone marrow and diěerentiate into the tissue-specięed cells. Furthermore, the data suggest that cell diěerentiation is due to Notch signaling. |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Edited by Thomas Heinbockel and Vonnie D.C. Shields : Published in London : IntechOpen, 2019. |
| 図書名 |
|
|
収録物名 |
Histology |
| 出版者 |
|
|
出版者 |
IntechOpen |
| ページ |
|
|
|
93-110 |
| 出版年月日 |
|
|
日付 |
2018-11-05 |
|
日付タイプ |
Issued |
| ISBN |
|
|
内容記述タイプ |
Other |
|
内容記述 |
978-1-78984-971-4 |
| 権利 |
|
|
権利情報 |
© 2018 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| 関連サイト |
|
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
https://dx.doi.org/10.5772/intechopen.80785 |
|
|
関連名称 |
IntechOpen |
| フォーマット |
|
|
内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
chapter6 (498.4 kB)
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