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加熱処理が球状ハイドロキシアパタイトの骨欠損部での骨伝導能に与える影響
https://mdu.repo.nii.ac.jp/records/538
https://mdu.repo.nii.ac.jp/records/538a798e309-2fa2-40f6-88ee-87e101a2ae96
名前 / ファイル | ライセンス | アクション |
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Item type | Journal Article(1) | |||||||
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公開日 | 2012-05-24 | |||||||
タイトル | ||||||||
タイトル | 加熱処理が球状ハイドロキシアパタイトの骨欠損部での骨伝導能に与える影響 | |||||||
言語 | ||||||||
言語 | jpn | |||||||
キーワード | ||||||||
主題Scheme | Other | |||||||
主題 | 骨補塡材 | |||||||
キーワード | ||||||||
主題Scheme | Other | |||||||
主題 | 焼成 | |||||||
キーワード | ||||||||
主題Scheme | Other | |||||||
主題 | 骨伝導 | |||||||
資源タイプ | ||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
資源タイプ | journal article | |||||||
その他(別言語等)のタイトル | ||||||||
その他のタイトル | The Effects of Heat Treatment of Spherical Hydroxyapatite Particles on Osteoconductivity in Bone Defects | |||||||
著者 |
渡邉, 敏之
× 渡邉, 敏之
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抄録 | ||||||||
内容記述タイプ | Abstract | |||||||
内容記述 | Hydroxyapatite (HAP) shows different characteristics depending on the sintering temperature. However, the effects of the heat treatments on bone formation ability in bone defects have not been well elucidated. To develop bone filling materials having higher tissue affinity and superior bone conductivity, we attempt in this study to clarify the histological processes of osteosynthesis and osteogenesis in response to various heat-treated spherical HAP particles filled in bone defects. Spherical-shaped HAP particles (ca/p of more than 1.7) were heat-treated at 800℃ and 900℃ for 60 and 1440 minutes. Each HAP particle was examined in bone defects (diameter 3mm) surgically created in the calvaria of male rats. Demineralized sections were made and observed by light microscopy. Some non-demineralized specimens were examined by scanning electron microscopy. At 7 days after implantation, new bone formation occurred from the surface of bone defected cavity in all experimental groups. At 14 days, newly formed bone was observed only around the HAP particles heat-treated at 800℃ for 1440 minutes (the 800/1440 group). Bone formation of the 800/1440 groups was more rapid than in the other experimental groups. Furthermore, in the 800/1440 group, the number of TRAP positive multinucleated cells (osteoclast-like cells) resorbing HAP particles was much greater than that in other experimental groups throughout the experimental period. These results demonstrate that 800/1440 HAP particles have superior osteoconductivity and bioresorbability and suggest they may be useful as a filling material for bone defects. | |||||||
書誌情報 |
松本歯学 巻 30, 号 3, p. 228-237, 発行日 2004-12-31 |
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出版者 | ||||||||
出版者 | 松本歯科大学学会 | |||||||
ISSN | ||||||||
収録物識別子タイプ | ISSN | |||||||
収録物識別子 | 0385-1613 | |||||||
書誌レコードID | ||||||||
収録物識別子タイプ | NCID | |||||||
収録物識別子 | AN00232590 | |||||||
フォーマット | ||||||||
内容記述タイプ | Other | |||||||
内容記述 | application/pdf | |||||||
著者版フラグ | ||||||||
出版タイプ | VoR | |||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |