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  1. 松本歯学(Print edition:ISSN 0385-1613 Online edition:ISSN 2188-7233)
  2. 29巻(2003)
  3. 2号

キトサンを結合体とした自己硬化型骨補填材の研究

https://mdu.repo.nii.ac.jp/records/585
https://mdu.repo.nii.ac.jp/records/585
785d1d30-58e8-428f-9a5d-adb06d66270b
名前 / ファイル ライセンス アクション
matsumoto_shigaku_29-02-03.pdf matsumoto_shigaku_29-02-03.pdf (2.6 MB)
Item type Journal Article(1)
公開日 2012-05-24
タイトル
タイトル キトサンを結合体とした自己硬化型骨補填材の研究
言語
言語 jpn
キーワード
主題Scheme Other
主題 キトサン
キーワード
主題Scheme Other
主題 骨補填材
キーワード
主題Scheme Other
主題 ハイドロキシアパタイト
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
その他(別言語等)のタイトル
その他のタイトル Study on self-hardening bone filling materials with chitosan as a binding agent
著者 中島, 三晴

× 中島, 三晴

中島, 三晴

抄録
内容記述タイプ Abstract
内容記述 A self-curing type of bone filling material has been developed by mixing chitosan solution and admixed powder. The chitosan solution was prepared by dissolving 85% de-acetyl chitosan and 99% deacetyl chitosan with organic acids, and the powder was a mixture of hydroxyapatite particles, CaO powder, and ZnO powder. The bone filling materials were compressed to form samples for compression tests. The Ca ions, P ions, Zn ions and pH value were measured. The main findings were as follows; 1. The compression strength of bone filling materials using 85% de-acetyl chitosan showed a maximum value of about 13 MPa at 1 day after immersion in physiological saline solution, followed by a continuous decrease down to 2 MPa. On the other hand, the bone filling material prepared with 99% de-acetyl chitosan did not show a remarkable decrease in compressive strength, however, it exhibited a continuous but smaller decrease by immersion time than the filling material prepored with 85% de-acetyl chitosan, because 85% de-acetyl chitosan gel could be more easily dissolved by 99% de-acetyl chitosan. 2. The changes in pH value of both 85% and 99% de-acetyl chitosan bone filling materials showed minimum values at 1 day after immersion, followed by a continuous increase with time, and the pH value of bone filling material containing 99% de-acetyl chitosan was higher than that with 85% de-acetyl chitosan material. 3. The dissolved Ca ions from the bone filling material with 85% de-acetyl chitosan reached its maximum at 28 days and minimum at 56 days after the immersion into physiological solution. The dissolved Ca ions from the bone filling material containing 99% de-acetyl chitosan exhibited its maximum at 1 day and its minimum at 28 days after the immersion, but there was no difference between these two types of materials. 4. The dissolved P ions from bone filling materials containing 85% and 99% de-acetyl chitosan had similar trends of continuous increase with time, and there was no difference between the two materials. 5. With regard to the dissolved Zn ions, the bone filling material made using 99% de-acetyl chitosan showed smaller values than that made with 85% de-acetyl chitosan, except at 56 days after the immersion.
書誌情報 松本歯学

巻 29, 号 2, p. 157-169, 発行日 2003-08-31
出版者
出版者 松本歯科大学学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 0385-1613
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00232590
フォーマット
内容記述タイプ Other
内容記述 application/pdf
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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