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  1. 松本歯学(Print edition:ISSN 0385-1613 Online edition:ISSN 2188-7233)
  2. 24巻(1998)
  3. 1号

血液レオロジーと微小循環について

https://mdu.repo.nii.ac.jp/records/737
https://mdu.repo.nii.ac.jp/records/737
c1c28d51-5ab0-4c92-a575-2bc99687c72e
名前 / ファイル ライセンス アクション
matsumoto_shigaku_24-01-01.pdf matsumoto_shigaku_24-01-01.pdf (835.1 kB)
Item type Journal Article(1)
公開日 2012-05-24
タイトル
タイトル 血液レオロジーと微小循環について
言語
言語 jpn
キーワード
言語 en
主題Scheme Other
主題 Blood Rheology
キーワード
言語 en
主題Scheme Other
主題 Microcirculation
キーワード
言語 en
主題Scheme Other
主題 Hematocrit
キーワード
言語 en
主題Scheme Other
主題 Prostagrandin E_1
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
その他(別言語等)のタイトル
その他のタイトル Blood Rheology and Microcirculation
著者 廣瀬, 伊佐夫

× 廣瀬, 伊佐夫

廣瀬, 伊佐夫

抄録
内容記述タイプ Abstract
内容記述 The science of rheology deals with the general flow and deformation behavior of all types of materials. There are two important properties of blood which characterize its rheological behavior, the blood viscosity function and the blood yield stress-shair rate. The whole blood viscosity shows the characteristics of a non-Newtonian fluid. These characteristics is necessary to understand the intricate peripheral blood flow function. Recently, the accumulated rheological knowledge is very vigorous applied in clinical medicine. Therefore, a brief review of blood rheology with fundamental theory on its application in surgery are present, and a some data which obtained by our experimental studies concerned with the blood viscosity on the circulatory system of the body, especially the microcirculation, the relationship between the viscosity characteristics and the peripheral tissue blood flow is shown with respect to blood rheology. Under the circulatory system in mongrel dogs, the peripheral tissue blood flow increase with Hct (systemic hematocrit) at all sites of measurement in the high Hct group, reached a peak of 1.39±0.24 at point where Hct was reached 1.14±0.08 relative control values. At higher Hct levels, the blood flow decreased; it was 0.66±0.14 at a maximum increase in Hct of 1.43±0.13. In the low Hct group, the blood flow tended to decrease with Hct. These results suggest that an increase in Hct to 1.14±0.08 as compared with a control value has a favorable effect on the microcirculation despite a increase in the blood viscosity and that a decrease in the blood flow of the microcirculation in spite of a decrease in both the whole blood and plasma viscosities. As the effect of Prostaglandin E, (PGE_1) to the tissue blood flow, PGE_1 improves the blood liquidity in the microcirculation system due to the membrane transmutability of the red blood cell, but that, in an ischemic lesion such as intestinal membrane, the blood flow more affected by the reduced mean arterial pressure than by the effect of low blood viscosity. Blood rheology is an interdiciplinary field, involving the application of knowledge derived from many disciplines of basic sciences to understanding of the pathophysiological roles and the therapeutic implications of blood rheology in clinical disorders or emphasis. Further advances in research on hemorheology requires an interdisciplinary approach.
書誌情報 松本歯学

巻 24, 号 1, p. 1-14, 発行日 1998-04-30
出版者
出版者 松本歯科大学学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 0385-1613
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00232590
フォーマット
内容記述タイプ Other
内容記述 application/pdf
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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