Heat shock proteins (HSPs) are induced by not only the heat shock but also the mechanical stress. Orthodontic tooth movement induced mechanical stress in the related periodontal ligament. It is important to examine the inununohistochemical profile change of the Heat shock proteins (HSPs) in the periodontal ligament cells after receiving the mechanical stress for orthodontic treatment. Therefore, we examined the HSPs in the periodontal ligament cells of ddY mice using the Waldo method. In the control group, periodontal ligament was observed as physiological anangement, and which reacted weakly to HSP27 and HSP70. In the experimental group the extension site of the periodontal ligament cells and the expansion of the blood vessel occuned in the traction side. These tissues were strongly reacted to HSP27 and HSP70. The findings suggeste that the HSPsexpression work as the mechanism of maintenance of homeostasis in the periodontal tissues.
雑誌名
Journal of Hard Tissue Biology
巻
18
号
4
ページ
193 - 197
発行年
2009-12
出版者
Society for Hard Tissue Regenerative Biology (硬組織再生生物学会)
歯科矯正学的メカニカルストレスによりマウス歯根膜組織に発現する熱ショックタンパクの免疫組織化学的観察
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