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Effects of Placental Extract on Cell Proliferation, Type I Collagen Production, and ALP Secretion in Human Osteosarcoma Cell Line Saos-2
https://mdu.repo.nii.ac.jp/records/2707
https://mdu.repo.nii.ac.jp/records/2707076a8813-b557-49f8-94c8-23845a480958
名前 / ファイル | ライセンス | アクション |
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本文 (697.5 kB)
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Item type | 松本歯学/学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-03-07 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Effects of Placental Extract on Cell Proliferation, Type I Collagen Production, and ALP Secretion in Human Osteosarcoma Cell Line Saos-2 | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 骨肉腫 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 胎盤抽出物 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 細胞増殖 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 腫瘍細胞系 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ヒト | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ブタ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 動物 | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | ALP | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Collagen | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Osteoblast | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Placenta | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Saos-2 | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Alkaline Phosphatase | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | ELISA | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Tetrazolium Salts | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Thiazoles | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Collagen Type I | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Thiazolyl Blue | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
その他(別言語等)のタイトル | ||||||
その他のタイトル | 胎盤抽出物がヒト骨肉腫細胞株Saos-2の細胞増殖、I型コラーゲン産生およびALP分泌に及ぼす効果 | |||||
著者 |
IMAMURA, YASUHIRO
× IMAMURA, YASUHIRO× HONDA, YOSHITOMO× MASUNO, KAZUYA× NAKAMURA, HIROE× WANG, PAO-LI |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Porcine placenta extract (P-placenta) is widely applied in medicine and cosmetics. However, few studies have examined the effect of the extract on the cellular behavior of the osteoblastic cell line Saos-2. Here, we demonstrated that P-placenta enhances the proliferation, collagen type I production, and alkaline phosphatase (ALP) secretion of Saos-2 in vitro. Proliferation of Saos-2 was assessed by MTT and DNA synthesis assays. Type I collagen production and ALP secretion were evaluated using enzyme-linked immunosorbent assay and ALP assays. The cells were treated with/without 20, 200 and 2000 g/ml of P-placenta for 24 h. We found that 200 g/ml P-placenta significantly induced the proliferation of Saos-2 and enhanced type I collagen production and ALP secretion. The results indicate that P-placenta controls the cellular behavior of osteoblasts, resulting in the secretion of early bone-related biomarkers. |
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書誌情報 |
en : Journal of Hard Tissue Biology 巻 26, 号 2, p. 157-160, 発行日 2017-04 |
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出版者 | ||||||
出版者 | Society for Hard Tissue Regenerative Biology (硬組織再生生物学会) | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1341-7649 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11074332 | |||||
NII論文ID | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | NAID | |||||
関連識別子 | 40021177219 | |||||
医中誌ID | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | ICHUSHI | |||||
関連識別子 | 2018007458 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.2485/jhtb.26.157 | |||||
関連名称 | info:doi/10.2485/jhtb.26.157 | |||||
権利 | ||||||
権利情報 | © 2017 by The Hard Tissue Biology Network Association(JHTBNet) | |||||
情報源 | ||||||
関連名称 | 雑誌掲載論文(電子版) | |||||
関連サイト | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.2485/jhtb.26.157 | |||||
関連名称 | Jstage | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |