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Effects of Sodium Fluoride on Frog Heart Motility
https://mdu.repo.nii.ac.jp/records/1395
https://mdu.repo.nii.ac.jp/records/1395407cc178-3f02-4c9a-9777-80785cfe04a3
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
matsumoto_shigaku_10-01-02.pdf (386.4 kB)
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| Item type | Journal Article(1) | |||||||
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| 公開日 | 2012-05-24 | |||||||
| タイトル | ||||||||
| タイトル | Effects of Sodium Fluoride on Frog Heart Motility | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | sodium fluoride | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | frog heart contraction | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | Ca^<++> influx | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | Na^+-Ca^<++> | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | exchange mechanism | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 著者 |
HATTORI, TOSHIMI
× HATTORI, TOSHIMI
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| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Effects of sodium fluoride (NaF) on the bullfrog heart were investigated. NaF (10 mM) inhibited the autonomic heart contraction, reducing the heart rate. This inhibitory action was recovered by per fusion with 2-Ca^<++> Ringer's solution. The twitch tension of auricular muscle was reduced by 2 mM NaF as well as 1 mM sodium oxalate and low-Ca^<++> Ringer, but the latter two were less effective than the former. However, NaF (5 mM) induced a rise in resting tension similar to that in the case of DNP application. ATP, adrenaline, and theophylline all reversed the inhibitory action of NaF, while both DNP and iodo acetic acid promoted it. NaF (5 mM) decreased the tension of Na^+-deficient contracture. The results obtained suggest that the reduction in the heart motility by NaF might be caused by the following mechanism : Inhibition of Ca^<++> influx into the myocardial cell as a result of both decrease in the extracellular Ca^<++> concentration and inhibition of ATP production and the Na^+-Ca^<++> exchange. | |||||||
| 書誌情報 |
松本歯学 巻 10, 号 1, p. 17-23, 発行日 1984-06-30 |
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| 出版者 | ||||||||
| 出版者 | 松本歯科大学学会 | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 0385-1613 | |||||||
| 書誌レコードID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AN00232590 | |||||||
| フォーマット | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | application/pdf | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
