WEKO3
アイテム
塩化第二水銀のラット肝薬物代謝酵素に対する作用
https://mdu.repo.nii.ac.jp/records/1699
https://mdu.repo.nii.ac.jp/records/1699b46fcbb3-5dfc-42dd-a6e6-cf487e0a1125
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
matsumoto_shigaku_07-02-03.pdf (270.8 kB)
|
|
| Item type | Journal Article(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2013-10-30 | |||||||
| タイトル | ||||||||
| タイトル | 塩化第二水銀のラット肝薬物代謝酵素に対する作用 | |||||||
| 言語 | ||||||||
| 言語 | jpn | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| その他（別言語等）のタイトル | ||||||||
| その他のタイトル | The Effect of Mercuric Choride on Drug-Metabolizing Enzymes in Rat Liver | |||||||
| 著者 |
倉橋, 寿
× 倉橋, 寿
|
|||||||
| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | The effect of mercuric chloride on drug-metabolizing enzymes in rat liver was studied in vivo and in vitro. In the in vitro study, when mercury was added to the incubation mixtures, all enzymes were inhibited. Fifty per cent inhibitory rate was 52 ppm on aminopyrine demethylase, 72 ppm on aniline hydroxylase, 96 ppm on hexobarbital oxidase respectively. In the in vivo study, when rats were ingested mercuric chloride in their drinking water for a month, the quantity of drinking water was decreased against the increase of mercury concentration. Body weight and liver-body weight ratio were also decreased. The concentration of mercury in rat liver was increased in direct proportion to the each quantity of mercury ingestion. Aminopyrine demethylase, aniline hydroxylase and hexobarbital oxidase were all inhibited as well. The inhibition was stronger in vivo under the same mercury concentration. | |||||||
| 書誌情報 |
松本歯学 巻 7, 号 2, p. 194-198, 発行日 1981-12-31 |
|||||||
| 出版者 | ||||||||
| 出版者 | 松本歯科大学学会 | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 0385-1613 | |||||||
| 書誌レコードID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AN00232590 | |||||||
| フォーマット | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | application/pdf | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
