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2回抽出法による血液中の局所麻酔剤の抽出とGas Chromatographによる分析
https://mdu.repo.nii.ac.jp/records/254
https://mdu.repo.nii.ac.jp/records/254f3caf6b7-ab3a-44ab-ba82-a75fcbcb76ce
名前 / ファイル | ライセンス | アクション |
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Item type | Journal Article(1) | |||||||
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公開日 | 2012-05-23 | |||||||
タイトル | ||||||||
タイトル | 2回抽出法による血液中の局所麻酔剤の抽出とGas Chromatographによる分析 | |||||||
言語 | ||||||||
言語 | jpn | |||||||
資源タイプ | ||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
資源タイプ | journal article | |||||||
その他(別言語等)のタイトル | ||||||||
その他のタイトル | The Twice Extracting Method of the Local Anesthetics in Human Blood for the Gas Chromatographic Study | |||||||
著者 |
礒, 勝彦
× 礒, 勝彦
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抄録 | ||||||||
内容記述タイプ | Abstract | |||||||
内容記述 | It has been thought important to study the concentration levels of the local anesthetics, because to which toxic symptoms induced by local anesthesia in the oral region is considered proportional. In the gas chromatographic studies for this purpose, it is necessary to refer to the method of extracting the local anesthetics in the blood plasma. We examined the two times extracting method, utilizing a peculiarity of that the local anesthetics being easily solved in organic solvent in alkaline solution and in water (aquaous layer) in acid solution. The specimen of blood containing local anesthetics was resolved with CCl_4 by stirring repeatedly with alkaline solution and acid solution. Consequently the peaks of the local anesthetics on the gas chromatogram (by GC-4BPTF, Shimadzu) showed that the mutual intervention of the organic substances in the blood was distinctly eliminated. The peak heights of the local anesthetics and the internal standard were measured and the ratios of them were compared with the control, and the regression lines were calculated. Thus the two times extracting method of the local anesthetics was confirmed to be valid in the gas chromatography. | |||||||
書誌情報 |
松本歯学 巻 6, 号 1, p. 95-99, 発行日 1980-06-30 |
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出版者 | ||||||||
出版者 | 松本歯科大学学会 | |||||||
ISSN | ||||||||
収録物識別子タイプ | ISSN | |||||||
収録物識別子 | 0385-1613 | |||||||
書誌レコードID | ||||||||
収録物識別子タイプ | NCID | |||||||
収録物識別子 | AN00232590 | |||||||
フォーマット | ||||||||
内容記述タイプ | Other | |||||||
内容記述 | application/pdf | |||||||
著者版フラグ | ||||||||
出版タイプ | VoR | |||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |