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ヒ素化合物による赤血球膜浸透圧抵抗の変化
https://mdu.repo.nii.ac.jp/records/267
https://mdu.repo.nii.ac.jp/records/267afe21f0f-4b75-41da-8bc9-c8d26c93bc98
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
matsumoto_shigaku_06-02-05.pdf (283.4 kB)
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| Item type | Journal Article(1) | |||||||
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| 公開日 | 2012-05-23 | |||||||
| タイトル | ||||||||
| タイトル | ヒ素化合物による赤血球膜浸透圧抵抗の変化 | |||||||
| 言語 | ||||||||
| 言語 | jpn | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| その他（別言語等）のタイトル | ||||||||
| その他のタイトル | Osmotic Fragility of Rat Erythrocytes Caused by Arsenic Compounds | |||||||
| 著者 |
都筑, 新太郎
× 都筑, 新太郎
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| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Coil planet centrifugation was used to measure osmotic fragility in rat erythrocytes treated with arsenic compounds in vitro and in vivo. Arsenic trioxide given orally to rats caused a significant increase in the osmotic fragility at a dose level of 20-120mg As/kg of body weight. However, in vitro tests on the erythrocytes, which were treated with 2-500μgAs/ml of blood for 1 hr. incubation at 37℃, no significant changes were observed. Monomethylarsonic acid and dimethylarsinic acid, known as metabolites of inorganic arsenic, induced no significant changes in the osmotic fragility in vitro tests on the erythrocytes. Moreover, these compounds did not show any changes even when rats received i. p. injection of 20mg As/kg of body weight. In case of sodium arsenate, oral administration of 60mg As/kg of body weight caused a significant increase in the osmotic fragility. In inducement of the osmotic fragility in the erythrocytes sodium arsenate appeared to be less active than arsenic trioxide. | |||||||
| 書誌情報 |
松本歯学 巻 6, 号 2, p. 173-178, 発行日 1980-12-31 |
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| 出版者 | ||||||||
| 出版者 | 松本歯科大学学会 | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 0385-1613 | |||||||
| 書誌レコードID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AN00232590 | |||||||
| フォーマット | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | application/pdf | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
