| Item type |
図書 / Book(1) |
| 公開日 |
2019-01-23 |
| タイトル |
|
|
タイトル |
Chapter 3 : Involvement of heat-shock proteins during periodontal logament remondeling. |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
periodontal ligament |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
mechanical stress |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
homeostasis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
heat-shock proteins |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
HSP |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
fibroblasts |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
collagen tissue |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
immunohistochemistry |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
occlusal trauma |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_2f33 |
|
資源タイプ |
book |
| 著者 |
MURAOKA, RINA
NAKANO, KEISUKE
TSUJIGIWA, HIDETSUGU
NAGATSUKA, HITOSHI
MATSUDA, HIROKAZU
TOMIDA, MIHOKO
OKAFUJI, NORIMASA
YAMADA, KAZUHIRO
KAWAKAMI, TOSHIYUKI
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Mechanical stress induces various molecules such as heat-shock protein (HSP), which
causes structural changes in the proteins in periodontal ligament (PDL). We carried out
an experiment to induce traumatic occlusion in mouse PDL and analyzed the expression of HSPs. HSPs investigated acts diff erently depending on the time of expression. HSPs are constitutively expressed in the PDL and defend cells from stress and maintain homeostasis under normal conditions. During bone addition to the PDL on the tension side, HSP27 and HSP47, HSP70 also acts as molecular chaperone, which assists the matu-ration of bone morphogenetic proteins and aids osteoblast activation. In HSP 70 and HSP 47, mechanical stress is applied to the PDL on the tension side for a short period of time for alveolar bone repairing, and when abnormality occurs in the collagen structure fi broblasts of PDL, it functions at the injured site, whereby extracellular that promotes abnormal collagen secretion and stores the modifi ed protein in the endoplasmic reticulum, there by controlling the decalcifi cation of PDL. In other words, HSP47 and HSP70 are expressed in PDL fi broblasts on the pressure side damaged by application of mechanical stress and contribute to the repair of collagen tissue by activating PDL fi broblasts, supporting recovery from cell damage. |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Edited by Jane Manakil,282p,illus. : London : IntechOpen, 2019. |
| 図書名 |
|
|
収録物名 |
Periodontology and Dental Implantology |
| 出版者 |
|
|
出版者 |
IntechOpen |
| ページ |
|
|
|
51-86 |
| 出版年月日 |
|
|
日付 |
2019 |
|
日付タイプ |
Issued |
| ISBN |
|
|
内容記述タイプ |
Other |
|
内容記述 |
9781789849325 |
| 権利 |
|
|
権利情報 |
© 2018 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| 関連サイト |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
http://dx.doi.org/10.5772/intechopen.79200 |
|
|
関連名称 |
IntechOpen |
| フォーマット |
|
|
内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
Chapter 3 (4.7 MB)
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