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砒素のラット肝薬物代謝酵素に対する影響
https://mdu.repo.nii.ac.jp/records/283
https://mdu.repo.nii.ac.jp/records/283bcc90760-69a2-4e06-a403-f0caed0816ef
名前 / ファイル | ライセンス | アクション |
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Item type | Journal Article(1) | |||||||
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公開日 | 2012-05-23 | |||||||
タイトル | ||||||||
タイトル | 砒素のラット肝薬物代謝酵素に対する影響 | |||||||
言語 | ||||||||
言語 | jpn | |||||||
資源タイプ | ||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
資源タイプ | journal article | |||||||
その他(別言語等)のタイトル | ||||||||
その他のタイトル | The Effect of Sodium Arsenite on Drug-Metabolizing Enzymes in Rat Liver | |||||||
著者 |
倉橋, 寿
× 倉橋, 寿
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抄録 | ||||||||
内容記述タイプ | Abstract | |||||||
内容記述 | The effect of sodium arsenite on drug-metabolizing enzymes in rat liver was studied in vivo and in vitro. In the in vitro study, aminopyrine demethylase, hexobarbital oxidase and aniline hydroxylase were all inhibited when sodium arsenite was added to the incubation mixtures. In the in vivo study, when rats were ingested sodium arsenite in their drinking water for a month, it was observed that the quantity of drinking water was decreased against the increase of arsenic concentration. The maximam intake of arsenic from drinking water was 9mg/kg/day. Body weight and liver-body weight ratio were rather increased in low arsenic concentration, but they were decreased in high concentration. The three of drug-metabolizing enzymes were inhibited as well. The inhibition was stronger in vivo under the same arsenic concentration. | |||||||
書誌情報 |
松本歯学 巻 7, 号 1, p. 64-67, 発行日 1981-06-30 |
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出版者 | ||||||||
出版者 | 松本歯科大学学会 | |||||||
ISSN | ||||||||
収録物識別子タイプ | ISSN | |||||||
収録物識別子 | 0385-1613 | |||||||
書誌レコードID | ||||||||
収録物識別子タイプ | NCID | |||||||
収録物識別子 | AN00232590 | |||||||
フォーマット | ||||||||
内容記述タイプ | Other | |||||||
内容記述 | application/pdf | |||||||
著者版フラグ | ||||||||
出版タイプ | VoR | |||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |