WEKO3
アイテム
ヒ素化合物のラット赤血球への移行
https://mdu.repo.nii.ac.jp/records/320
https://mdu.repo.nii.ac.jp/records/320ccd9039b-1a2d-4307-aa3d-1bd3a1a2b1fa
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
matsumoto_shigaku_08-01-05.pdf (271.5 kB)
|
|
| Item type | Journal Article(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2012-05-23 | |||||||
| タイトル | ||||||||
| タイトル | ヒ素化合物のラット赤血球への移行 | |||||||
| 言語 | ||||||||
| 言語 | jpn | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| その他（別言語等）のタイトル | ||||||||
| その他のタイトル | Binding of Arsenic to Erythrocytes of Rats in vivo and in vitro | |||||||
| 著者 |
前橋, 浩
× 前橋, 浩
|
|||||||
| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | In measuring the osmotic fragility of rat erythrocytes by centrifugation using coil planet centrifuge, it was found that arsenic trioxide given orally to rats caused a significant increase in the osmotic fragility. However, in vitro tests on the erythrocytes in which one ml of blood was incubated with arsenic trioxide equivalent to 2～500μg of arsenic at 37℃ for 1 hr, no significant changes were observed. Monomethylarsonic acid and dimethylarsinic acid, known as metabolites of inorganic arsenic, induced no significant changes in the osmotic fragility in vitro tests on erytherocytes. The arsenic concentration in erythrocytes was measured in the tests in vitro and in vivo using flameless atomic absorption spectrometry. When arsenic was given orally to rats, more than 90% of arsenic in whole blood was found in erythrocytes. However, in vitro tests, only 30.4～47.5% was detected on erythrocytes even after 6 hrs incubation. These results obtained in relation to arsenic concentration may explain the effect of the arsenic on the osmotic fragility of rat erythrocytes. | |||||||
| 書誌情報 |
松本歯学 巻 8, 号 1, p. 51-55, 発行日 1982-06-30 |
|||||||
| 出版者 | ||||||||
| 出版者 | 松本歯科大学学会 | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 0385-1613 | |||||||
| 書誌レコードID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AN00232590 | |||||||
| フォーマット | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | application/pdf | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
