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口腔内Heparinase産生性BacteroidesのEndotoxinの生物学的活性
https://mdu.repo.nii.ac.jp/records/38
https://mdu.repo.nii.ac.jp/records/38c7521227-4390-48b6-8d28-a5e195554147
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
matsumoto_shigaku_02-01-02.pdf (749.0 kB)
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| Item type | Journal Article(1) | |||||||
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| 公開日 | 2012-04-27 | |||||||
| タイトル | ||||||||
| タイトル | 口腔内Heparinase産生性BacteroidesのEndotoxinの生物学的活性 | |||||||
| 言語 | ||||||||
| 言語 | jpn | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| その他（別言語等）のタイトル | ||||||||
| その他のタイトル | Biological Activity of Endotoxin from Oral Heparinase-producing Bacteroides | |||||||
| 著者 |
中村, 武
× 中村, 武
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| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | A possible role of oral Heparinase-producing Bacteroides which resembles to Bacteroides oralis in the character in the etiology of periodontal disease has been emphasized by the authors. This is mainly based on the facts that they possessed heparinase and remarkably increase in number in the local samples of experimental mixed infection by human dental plaque following serial transfer. The present study dealed with the extraction and characterization of the endotoxin from the cells of the Bacteroides. Three strains which differed from each other in the heparinase activity were grown in Trypticase broth for 5 days anaerobically at 37℃. Harvested cells were washed three times with acetone, dried under CaCl_2 and subjected to extraction. Endotoxin were extracted by phenol-water (1:1) according to Westphal method with some modifications. The recoveries of preparation were 7～17% by dry weight basis. Preparations were whitish powder and water-soluble. Preparations pyrogenicity, Shwartzman reactive activity and cytotoxic activity of the endotoxin were demonstrated. The higher endotoxic activity was observed in the preparation with higher recovery. In the Shwartzman reaction, a positive correlation was found between preparatory activity of the endotoxin and the heparinase activity of the strain. | |||||||
| 書誌情報 |
松本歯学 巻 2, 号 1, p. 12-19, 発行日 1976-06-30 |
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| 出版者 | ||||||||
| 出版者 | 松本歯科大学学会 | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 0385-1613 | |||||||
| 書誌レコードID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AN00232590 | |||||||
| フォーマット | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | application/pdf | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
